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Lenalidomide Accord 5 mg hard capsules

DRUG8 trials

Sponsors

Janssen - Cilag International, European Myeloma Network B.V., Emn Trial Office S.r.l. Impresa Sociale, Kartos Therapeutics Inc.

Conditions

Multiple MyelomaNewly Diagnosed Multiple MyelomaPrimary Or Secondary (Post-PV MF or Post-ET-MF) Myelofibrosis (MF) With Intermediate Or High-Risk TP53 Wild-Type (TP53 WT) Who Are Relapsed Or Refractory to Janus Kinase (JAK) - Inhibitor TreatmentRelapsed/Refractory Mantle Cell Lymphoma

Phase 2

A Phase 2, Multi-cohort Study Applying Innovative MRD Techniques for Transplant Eligible Participants with Previously Untreated Multiple Myeloma - TAURUS
RecruitingCTIS2023-505221-14-00
European Myeloma Network B.V., Emn Trial Office S.r.l. Impresa SocialeMultiple Myeloma
Start: 2023-12-04Target: 237Updated: 2026-01-26
A Randomized, Controlled, Open-label, Multicenter, Inferentially Seamless Phase 2/3 Study of Ibrutinib in Combination With Rituximab Versus Physician’s Choice of Lenalidomide Plus Rituximab or Bortezomib Plus Rituximab in Participants with Relapsed or Refractory Mantle Cell Lymphoma
CompletedCTIS2023-503618-64-00
Janssen - Cilag InternationalRelapsed/Refractory Mantle Cell Lymphoma
Start: 2022-11-16End: 2024-09-18Target: 7Updated: 2024-04-24
A Phase 2, Multicohort Open-Label Study of JNJ-68284528, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA in Subjects with Multiple Myeloma CARTITUDE-2
Active, not recruitingCTIS2023-506587-13-00
Janssen - Cilag InternationalMultiple Myeloma
Start: 2020-01-30Target: 56Updated: 2025-09-02
A Phase 2/3 Randomized, Controlled, Open-Label Study of KRT 232 in Subjects with Primary Myelofibrosis (PMF), Post Polycythemia Vera MF (Post-PV-MF), Or Post Essential Thrombocythemia MF (Post-ET-MF) who are Relapsed or Refractory to Janus Kinase (JAK) Inhibitor Treatment
Active, not recruitingCTIS2024-513912-89-00
Kartos Therapeutics Inc.Primary Or Secondary (Post-PV MF or Post-ET-MF) Myelofibrosis (MF) With Intermediate Or High-Risk TP53 Wild-Type (TP53 WT) Who Are Relapsed Or Refractory to Janus Kinase (JAK) - Inhibitor Treatment
Start: 2018-12-13Target: 253Updated: 2025-09-17

Phase 3

A Phase 3 Randomized Study Comparing Bortezomib, Lenalidomide and Dexamethasone (VRd) followed by Ciltacabtagene Autoleucel, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA versus Bortezomib, Lenalidomide, and Dexamethasone (VRd) followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants with Newly Diagnosed Multiple Myeloma for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy.
Active, not recruitingCTIS2023-505850-16-00
Janssen - Cilag InternationalMultiple Myeloma
Start: 2021-08-05Target: 371Updated: 2026-01-19
A Phase 3 Randomized Study Comparing Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) followed by Ciltacabtagene Autoleucel versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) followed by Autologous Stem Cell Transplant (ASCT) in Participants with Newly Diagnosed Multiple Myeloma who are Transplant Eligible
Not yet recruitingCTIS2023-507632-20-00
European Myeloma Network B.V., Emn Trial Office S.r.l. Impresa SocialeMultiple Myeloma
Target: 440Updated: 2026-01-13
Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation – MajesTEC-4
RecruitingCTIS2023-510384-36-00
European Myeloma Network B.V., Emn Trial Office S.r.l. Impresa SocialeNewly Diagnosed Multiple Myeloma
Start: 2022-09-13Target: 1107Updated: 2025-10-29
A Phase 3 Randomized Study Comparing Teclistamab in Combination with Daratumumab SC and Lenalidomide (Tec-DR) and Talquetamab in Combination with Daratumumab SC and Lenalidomide (Tal-DR) versus Daratumumab SC, Lenalidomide, and Dexamethasone (DRd) in Participants with Newly Diagnosed Multiple Myeloma Who are Either Ineligible or not Intended for Autologous Stem Cell Transplant as Initial Therapy
RecruitingCTIS2023-503442-30-00
Janssen - Cilag InternationalMultiple Myeloma
Start: 2022-10-14Target: 563Updated: 2025-09-02