Ledipasvir/Sofosbuvir

DRUG9 trials

Conditions

Chronic Hepatitis CChronic Hepatitis C InfectionCirrhosisCirrhosis, DecompensatedGaucher DiseaseHBV CoinfectionHCVHIV-1 Infection

Phase 1

Sofosbuvir-Containing Regimens Without Interferon For Treatment of Acute Hepatitis C Virus (HCV) Infection

CompletedNCT02128217

Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsHepatitis, HIV-1 Infection

Start: 2014-05-30End: 2017-05-09Updated: 2018-04-27

Study of Hepatitis C Treatment During Pregnancy

CompletedNCT02683005

Catherine ChappellHepatitis C, Pregnancy

Start: 2016-09-30End: 2020-02-03Updated: 2020-03-04

Phase 2

DAAs Treatment for Chronic HCV/HBV Co-infection Patients(DASCO)

CompletedNCT02555943

Humanity and Health Research CentreChronic Hepatitis C Infection, HBV Coinfection, Hepatitis B Reactivation

Start: 2015-02-28End: 2021-08-31Updated: 2021-09-01

12 Weeks of Ledipasvir (LDV)/Sofosbuvir (SOF) With Weight-based Ribavirin vs. 24 Weeks of LDV/SOF

TerminatedNCT02605304

Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsHepatitis C, HIV-1 Infection

Start: 2016-02-17End: 2017-03-20Updated: 2018-05-02

Phase 3

Sofosbuvir Containing Regimens for the Treatment of Chronic HCV GT3 Infected Patients

CompletedNCT02576314

Humanity and Health Research CentreChronic Hepatitis C Infection

Start: 2015-05-31End: 2018-03-15Updated: 2018-03-19

Effects of Harvoni in Patients With Decompensated Cirrhosis Due to Hepatitis C Genotype 1 Infection

CompletedNCT02597166

University Health Network, TorontoCirrhosis, Decompensated, Hepatitis C, Chronic

Start: 2016-01-31End: 2018-06-30Updated: 2018-10-25

Phase 4

Chronic Hepatitis C Treatment in Egyptian Children With Gaucher Disease.

NCT03721627

Mansoura University Children HospitalGaucher Disease, HCV

Start: 2018-04-03End: 2019-10-31Target: 10Updated: 2018-10-30

Unknown Phase

Impact of Antiviral Therapy on Gastroesophageal Varices.

CompletedNCT02758509

Parc de Salut MarChronic Hepatitis C, Cirrhosis

Start: 2010-01-01End: 2017-10-15Updated: 2018-05-21

The Effect of Direct Antiviral Therapy on Hepatitis c Virus-related Thrombocytopenia

NCT03169348

Assiut UniversityHepatitis C

Start: 2017-11-01End: 2019-09-30Target: 50Updated: 2017-12-07

The Egyptian Journal of Haematology2025-04-01

Ledipasvir plus sofosbuvir in pregnant women with hepatitis C virus infection: a phase 1 pharmacokinetic study.

2020-07-2775 citations

Impact of sustained virological response with DAAs on gastroesophageal varices and Baveno criteria in HCV-cirrhotic patients.

2019-09-0615 citations

Ledipasvir/Sofosbuvir for 8 Weeks to Treat Acute Hepatitis C Virus Infections in Men With Human Immunodeficiency Virus Infections: Sofosbuvir-Containing Regimens Without Interferon for Treatment of Acute HCV in HIV-1 Infected Individuals

Clinical Infectious Diseases2018-11-1227 citations

Sofosbuvir Plus Ribavirin Without Interferon for Treatment of Acute Hepatitis C Virus Infection in HIV-1–Infected Individuals: SWIFT-C

Clinical Infectious Diseases2017-01-3049 citations