LCAR-AIO T cells

BIOLOGICAL3 trials

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Nanjing Legend Biotech Co.

Conditions

Anti-Myelin Oligodendrocyte Glycoprotein-IgG Associated Disorders (MOGAD)Multiple Sclerosis (MS)Myasthenia GravisNeuromyelitis Optica Spectrum Disease (NMOSD)Relapsed/Refractory Autoimmune DiseasesSystemic Lupus Erythematosus (SLE)

Early Phase 1

A Study of LCAR-AIO in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus

RecruitingNCT06653556

Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologySystemic Lupus Erythematosus (SLE)

Start: 2025-01-08End: 2029-09-30Target: 34Updated: 2025-01-10

A Study of LCAR-AIO in Subjects With Relapsed/Refractory Autoimmune Diseases

WithdrawnNCT06866080

Nanjing Legend Biotech Co.Relapsed/Refractory Autoimmune Diseases

Start: 2025-06-17End: 2025-06-17Updated: 2025-07-08

Phase 1

A Study of LCAR-AIO CAR-T Cells for Treating Relapsed/Refractory Neurological Autoimmune Diseases

WithdrawnNCT06869278

Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyAnti-Myelin Oligodendrocyte Glycoprotein-IgG Associated Disorders (MOGAD), Multiple Sclerosis (MS), Myasthenia Gravis +1

Start: 2025-06-17End: 2025-06-17Updated: 2026-06-24