Larotrectinib (Vitrakvi, BAY2757556)
Sponsors
Bayer
Conditions
Advanced or Recurrent Solid Tumor Harboring an NTRK Gene FusionInfantile FibrosarcomaLocally Advanced or Metastatic Infantile Fibrosarcoma Harboring an NTRK Gene FusionSolid Tumors Harboring NTRK FusionTumors Harboring NTRK Fusion
Phase 1
A Study to Test the Safety of the Investigational Drug Larotrectinib in Adults That May Treat Cancer
CompletedNCT02122913
Start: 2014-05-04End: 2021-04-09Updated: 2026-02-05
A Study to Test the Safety and Efficacy of the Drug Larotrectinib for the Treatment of Tumors With NTRK-fusion in Children
Active, not recruitingNCT02637687
Start: 2015-12-16End: 2026-09-30Updated: 2025-06-22
Unknown Phase
Expanded Access to Provide Larotrectinib for the Treatment of Cancers With a NTRK Gene Fusion
NCT03025360
Updated: 2019-12-19
NTRK Gene Fusion - Positive Advanced or Recurrent Solid Tumors, a Rare Cancer Caused by Specific Changes in the Genes
RecruitingNCT04945330
Start: 2021-11-05End: 2029-12-31Target: 100Updated: 2026-07-07
A Study Called EPI VITRAKVI to Compare Treatment Results in Patients With Infantile Fibrosarcoma (IFS), a Type of Connective Soft Tissue Cancer, Who Received a Treatment Called Larotrectinib From a Study Called SCOUT With Patient Data From an External Database
CompletedNCT05236257
Start: 2022-03-10End: 2022-09-13Updated: 2024-12-10
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