Lapine T-Lymphocyte Immune Globulin

BIOLOGICAL6 trials

Conditions

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAnaplastic EpendymomaAtypical Teratoid/Rhabdoid TumorBeta Thalassemia MajorBone Marrow Failure SyndromeCentral Nervous System Germ Cell TumorChoroid Plexus Carcinoma

Early Phase 1

Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies

WithdrawnNCT04776850

M.D. Anderson Cancer CenterBeta Thalassemia Major, Sickle Beta 0 Thalassemia, Sickle Beta Plus Thalassemia +3

Start: 2020-12-29End: 2022-12-05Updated: 2024-10-24

Phase 1

Total Body Irradiation and Astatine-211-Labeled BC8-B10 Monoclonal Antibody for the Treatment of Nonmalignant Diseases

RecruitingNCT04083183

Fred Hutchinson Cancer CenterNon-Malignant Neoplasm

Start: 2020-06-16End: 2028-01-09Target: 40Updated: 2025-12-18

Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer

WithdrawnNCT04521946

M.D. Anderson Cancer CenterAnaplastic Ependymoma, Atypical Teratoid/Rhabdoid Tumor, Central Nervous System Germ Cell Tumor +12

Start: 2021-01-14End: 2022-12-20Updated: 2024-10-26

Phase 2

Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults

TerminatedNCT04530487

M.D. Anderson Cancer CenterDesmoplastic Small Round Cell Tumor, Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Recurrent Desmoplastic Small Round Cell Tumor +9

Start: 2020-08-19End: 2024-08-26Updated: 2025-06-29

Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

CompletedNCT04965597

Fred Hutchinson Cancer CenterBone Marrow Failure Syndrome, Congenital Amegakaryocytic Thrombocytopenia, Diamond-Blackfan Anemia +6

Start: 2022-04-19End: 2026-02-18Updated: 2026-03-09

Phase 3

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Active, not recruitingNCT05457556

Children's Oncology GroupAcute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia +1