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LAIV

BIOLOGICAL7 trials

Sponsors

University of North Carolina, Chapel Hill, Marshfield Clinic Research Foundation, University of California, Los Angeles, Stanford University, Jiangsu Province Centers for Disease Control and Prevention

Conditions

COPDHabitsImmune Response to Influenza VaccineInfluenzaInfluenza A Virus InfectionInfluenza B Virus InfectionInfluenza, HumanRespiratory Tract Infections

Early Phase 1

Responses to Live Attenuated Influenza Virus (LAIV) in Chronic Obstructive Pulmonary Disease (COPD)
CompletedNCT04901455
University of North Carolina, Chapel HillCOPD
Start: 2022-10-03End: 2026-02-16Updated: 2026-02-24

Phase 1

Bacterial Composition and Immune Responses in the Nose and Oropharynx During Influenza Infection
CompletedNCT02597647
University of California, Los AngelesInfluenza
Start: 2011-02-01End: 2014-04-01Updated: 2026-01-22

Phase 4

Randomized Study of Immune Response to Licensed Influenza Vaccines in Children and Adolescents
CompletedNCT02250274
Marshfield Clinic Research FoundationImmune Response to Influenza Vaccine, Influenza A Virus Infection, Influenza B Virus Infection
Start: 2014-09-30End: 2015-04-30Updated: 2018-04-26
T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) Year 4, 2012
CompletedNCT03022435
Stanford UniversityInfluenza
Start: 2012-10-31End: 2013-01-31Updated: 2017-05-22
Mucosal and Systemic Immune Responses Induced by an Intranasal Influenza Live Attenuated Vaccine
Active, not recruitingNCT07232745
Jiangsu Province Centers for Disease Control and PreventionInfluenza
Start: 2025-10-12End: 2026-05-10Target: 60Updated: 2025-11-18
A Study on Mucosal Specific IgA Immunokinetics After Administration of Nasal Spray Live Attenuated Influenza Vaccine
Enrolling by invitationNCT07545564
Changchun BCHT Biotechnology Co.Influenza
Start: 2026-04-09End: 2026-05-09Target: 200Updated: 2026-04-22

Unknown Phase

Effects of Tobacco Products on Live Attenuated Influenza Virus (LAIV) Infections in Human Volunteers
CompletedNCT02019745
University of North Carolina, Chapel HillHabits, Influenza, Human, Respiratory Tract Infections +1
Start: 2014-06-30End: 2016-06-30Updated: 2018-04-04

Related Papers

Electronic-Cigarette Use Alters Nasal Mucosal Immune Response to Live-attenuated Influenza Virus. A Clinical Trial.
2021-01-0155 citations
The administration of intranasal live attenuated influenza vaccine induces changes in the nasal microbiota and nasal epithelium gene expression profiles
Microbiome2015-12-0178 citations