L-ornithine L-aspartate

DRUG9 trials

Conditions

Acute Liver FailureBreast CancerCirrhosisCirrhosis of LiverHepatic EncephalopathyHepatic Encephalopathy Stage 2Hepatic Encephalopathy Stage 3Hepatic Encephalopathy Stage 4

Phase 2

Therapeutic Efficacy of L-Ornithine L-Aspartate Infusion in Patients With Acute Liver Failure

NCT00470314

All India Institute of Medical SciencesAcute Liver Failure

Start: 2005-01-31End: 2007-05-31Updated: 2008-01-07

An Open-Label, Bayesian Adaptive Phase II Clinical Study in HR+/HER2- Advanced Breast Cancer After Progression on Standard Therapy

RecruitingNCT07117630

Fudan UniversityBreast Cancer

Start: 2025-09-25End: 2027-08-01Target: 40Updated: 2026-05-19

Phase 3

Efficacy of L-Ornithine-L-Aspartate in Cirrhotics With Hepatic Encephalopathy

CompletedNCT00433368

Aga Khan UniversityHepatic Encephalopathy

Start: 2003-10-31End: 2004-09-30Target: 108Updated: 2007-02-09

Phase 4

L-ornithine L-aspartate in Overt Hepatic Encephalopathy

CompletedNCT01722578

Dayanand Medical College and HospitalCirrhosis of Liver, Hepatic Encephalopathy

Start: 2013-12-31End: 2017-01-31Updated: 2017-02-08

Lactulose, L-ornithine L-aspartate, or Rifaximin Versus Placebo for Preventing Hepatic Encephalopathy in Variceal Bleeding

CompletedNCT02158182

Hospital General de MexicoHepatic Encephalopathy

Start: 2014-07-31End: 2016-06-30Updated: 2018-05-22

Effect of L-ornithine-L-aspertate (LOLA) on the Gut Microbiome

Active, not recruitingNCT05737030

Medical University of GrazCirrhosis

Start: 2023-02-06End: 2025-12-31Target: 55Updated: 2025-02-10

Efficacy of L-Ornithine L-Aspartate and Polyethylene Glycol in Cirrhotic Patients With Overt Hepatic Encephalopathy

NCT05920213

Jinnah Postgraduate Medical CentreHepatic Encephalopathy Stage 2, Hepatic Encephalopathy Stage 3, Hepatic Encephalopathy Stage 4

Start: 2023-10-31End: 2024-04-30Target: 360Updated: 2023-07-13

Unknown Phase

Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment.

CompletedNCT00305591

Imperial College LondonCirrhosis, Hepatic Encephalopathy

Start: 2006-03-31End: 2007-10-31Target: 50Updated: 2015-05-29

Efficacy of L-ornithine L-aspartate and Therapeutic Plasma Exchange Versus Plasma Exchange Alone in Lowering Ammonia and Improving Outcomes in Pediatric Acute Liver Failure.

NCT05778461

Institute of Liver and Biliary Sciences, IndiaLiver Failure, Acute

Start: 2023-03-15End: 2024-10-30Target: 32Updated: 2023-03-21

Related Papers

An observational study on the effect of l-ornithine-l-aspartate (LOLA) on the gut microbiome in liver cirrhosis. A single center phase 4 study.

2025-11-29

Primary Prophylaxis to Prevent the Development of Hepatic Encephalopathy in Cirrhotic Patients with Acute Variceal Bleeding

Canadian Journal of Gastroenterology and Hepatology2018-07-1042 citations

Efficacy of L-ornithine L-aspartate in acute liver failure: a double-blind, randomized, placebo-controlled study.

2009-06-01114 citations