Kyprolis 10 mg powder for solution for infusion

DRUG4 trials

Sponsors

University Medical Center Hamburg-Eppendorf, Kite Pharma Inc., Medizinische Universitaet Innsbruck, Regeneron Pharmaceuticals Inc.

Conditions

Multiple myelomaRelapsed Refractory Multiple MyelomaRelapsed/refractory multiple myeloma in patients who have received 1 to 3 prior lines of therapy and have been exposed to both an immunomodulatory drug and an anti-CD38 monoclonal antibodymultiple myeloma

Phase 2

Daratumumab in combination with Carfilzomib, Pomalidomide and Dexamethasone (DCPD) in patients with multiple myeloma induced acute renal failure - "Time is Kidney in the Treatment of myeloma Cast nephropathy" The TIKTAC phase II trial (Pilot-study)

Not yet recruitingCTIS2024-514702-31-00

Medizinische Universitaet InnsbruckMultiple myeloma

Target: 50Updated: 2024-10-29

Phase 3

Allogeneic stem cell transplantation vs. conventional therapy as salvage therapy for relapsed / progressive patients with multiple myeloma after a first-line therapy

CompletedCTIS2024-510590-14-00

University Medical Center Hamburg-Eppendorfmultiple myeloma

Start: 2023-03-03End: 2025-01-30Target: 400Updated: 2025-02-05

A Phase 3, Randomized, Open-Label Study to Compare the Efficacy and Safety of Anitocabtagene Autoleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Multiple Myeloma

RecruitingCTIS2024-511188-26-00

Kite Pharma Inc.Relapsed/refractory multiple myeloma in patients who have received 1 to 3 prior lines of therapy and have been exposed to both an immunomodulatory drug and an anti-CD38 monoclonal antibody

Start: 2024-12-20Target: 192Updated: 2025-09-12

An Open-label, Randomized Phase 3 Study of Linvoseltamab Monotherapy and Linvoseltamab plus Carfilzomib versus Standard of Care Combination Regimens in Patients with Relapsed/Refractory Multiple Myeloma

Not yet recruitingCTIS2024-519504-27-00

Regeneron Pharmaceuticals Inc.Relapsed Refractory Multiple Myeloma

Target: 40Updated: 2026-02-10