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KT-621

DRUG9 trials

Sponsors

Kymera Therapeutics Inc., Kymera Therapeutics, Inc.

Conditions

Asthma (Diagnosis)Atopic DermatitisEosinophilic AsthmaHealthy ParticipantsHealthy Participants StudyModerate to Severe Atopic DermatitisUncontrolled Moderate to Severe Eosinophilic Asthma

Phase 1

Phase 2

A Study of KT-621 Administered Orally to Participants With Moderate to Severe Atopic Dermatitis
Active, not recruitingNCT07217015
Kymera Therapeutics, Inc.Atopic Dermatitis
Start: 2025-11-24End: 2028-06-01Target: 200Updated: 2026-06-30
A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
RecruitingNCT07323654
Kymera Therapeutics, Inc.Eosinophilic Asthma
Start: 2026-01-28End: 2027-12-01Target: 264Updated: 2026-08-17
A Phase 2b, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter, Dose-ranging Study With an Open-label Period Investigating the Efficacy and Safety Profile of KT-621 Administered Orally to Participants with Moderate to Severe Atopic Dermatitis
Not yet recruitingCTIS2025-522370-36-00
Kymera Therapeutics Inc.Moderate to Severe Atopic Dermatitis
Target: 108Updated: 2026-01-19
A Phase 2b, Randomized, Double blind, Placebo controlled, Parallel group, Multicenter, Dose ranging Study Investigating the Efficacy and Safety Profile of KT-621 Administered Orally to Adult Participants with Uncontrolled Moderate to Severe Eosinophilic Asthma
Not yet recruitingCTIS2025-523180-38-00
Kymera Therapeutics Inc.Uncontrolled Moderate to Severe Eosinophilic Asthma
Target: 9Updated: 2026-04-10
A Long-term Study of KT-621 Administered Orally to Participants With Asthma Previously Enrolled in a KT-621 Asthma Study
RecruitingNCT07677059
Kymera Therapeutics, Inc.Asthma (Diagnosis)
Start: 2026-07-01End: 2028-12-01Target: 264Updated: 2026-06-30
A Multicenter, Open-Label, Long-Term Extension Study to Evaluate the Long Term Safety and Tolerability of KT-621 in Participants With Asthma Previously Enrolled in a KT-621 Asthma Study
Not yet recruitingCTIS2026-526241-98-00
Kymera Therapeutics Inc.Uncontrolled Moderate to Severe Eosinophilic Asthma
Target: 25Updated: 2026-09-09