Kratom

DIETARY_SUPPLEMENT4 trials

Sponsors

Washington State University, Altasciences Company Inc., Faculty of Medicine Ramathibodi Hospital, Mahidol University

Conditions

Chronic usersHerbal InteractionInteraction Drug FoodPharmacodynamicsPharmacokineticsSafety

Early Phase 1

Assessing the Pharmacokinetics and Drug Interaction Liability of Kratom, an Opioid-like Natural Product

CompletedNCT04392011

Washington State UniversityInteraction Drug Food

Start: 2019-10-09End: 2021-08-31Updated: 2023-12-20

Evaluating a Potential Pharmacokinetic Kratom-oxycodone Interaction Concurrent With Clinical Endpoints

RecruitingNCT05846451

Washington State UniversityHerbal Interaction

Start: 2023-06-01End: 2026-12-01Target: 16Updated: 2026-06-03

Phase 1

Pharmacokinetics of Kratom in Man

RecruitingTCTR20140908001

Faculty of Medicine Ramathibodi Hospital, Mahidol UniversityChronic users

Start: 2013-07-06Updated: 2026-08-03

Single Ascending Doses of Kratom in Healthy Nondependent Adults With Opioid Experience

CompletedNCT06072170

Altasciences Company Inc.Pharmacodynamics, Pharmacokinetics, Safety

Start: 2023-08-16End: 2024-01-23Updated: 2025-09-29