Kineret

DRUG7 trials

Conditions

Autoimmune DiseasesChronic Granulomatous DiseaseChronic Lymphocytic LeukemiaDiabetes MellitusEnd Stage Renal DiseaseFamilial Mediterranean FeverInflammatory DiseaseMacrophage Activation Syndrome

Early Phase 1

IL-1 Receptor Inhibitor for Granulomatous Complications in Patients With Chronic Granulomatous Disease

CompletedNCT04136028

Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyChronic Granulomatous Disease

Start: 2015-09-25End: 2020-01-31Target: 13Updated: 2020-04-07

Phase 1

Treatment of Macrophage Activation Syndrome (MAS) With Anakinra

TerminatedNCT02780583

University of Alabama at BirminghamMacrophage Activation Syndrome

Start: 2016-05-15End: 2024-04-30Updated: 2024-08-01

Anakinra in Previously Untreated Chronic Lymphocytic Leukemia Patients

NCT04691765

Dr. David SpanerChronic Lymphocytic Leukemia

Start: 2021-05-01End: 2022-12-31Target: 12Updated: 2021-03-19

Phase 2

Effect of Anakinra on Insulin Sensitivity in Type 1 Diabetes Mellitus

NCT01285245

Radboud University Medical CenterDiabetes Mellitus

Start: 2011-04-30End: 2011-12-31Target: 16Updated: 2011-04-14

Personalized Therapies in Inflammatory Complex Disease

RecruitingNCT03651518

Assistance Publique - Hôpitaux de ParisAutoimmune Diseases, Inflammatory Disease

Start: 2020-10-20End: 2025-11-30Target: 32Updated: 2025-11-20

Phase 3

Kineret (Anakinra), in Adult Patients With Colchicine-Resistant Familial Mediterranean Fever

CompletedNCT01705756

Sheba Medical CenterFamilial Mediterranean Fever

Start: 2012-11-30End: 2015-06-30Updated: 2024-04-02

Unknown Phase

Inflammation, Proteolysis and IL-1 Beta Receptor Inhibition in Chronic Hemodialysis Patients

CompletedNCT00420290

Vanderbilt UniversityEnd Stage Renal Disease

Start: 2008-01-31End: 2010-05-31Updated: 2011-11-17

Related Papers

IL-1 receptor antagonism reveals a yin-yang relationship between NFκB and interferon signaling in chronic lymphocytic leukemia

Proceedings of the National Academy of Sciences2024-08-092 citations

Macrophage Activation-Like Syndrome: A Distinct Entity Leading to Early Death in Sepsis.

2019-01-31218 citations