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Ketamine (0.5 mg/kg)

DRUG6 trials

Sponsors

Washington University School of Medicine, Children's Cancer Hospital Egypt 57357, Assiut University, Soterix Medical, Dr. Lutfi Kirdar Kartal Training and Research Hospital

Conditions

Anesthesia, GeneralBrain TumorDeliriumDepression DisorderElectroconvulsive TherapyEpilepsyKetamineTreatment Resistant Depression (TRD)

Phase 1

Ketamine Biomarker Validation
Not yet recruitingNCT07307768
Soterix MedicalTreatment Resistant Depression (TRD)
Start: 2025-12-20End: 2028-03-01Target: 20Updated: 2025-12-29

Phase 2

Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients
RecruitingNCT07639359
Hospital Italiano de Buenos AiresDepression Disorder, Ketamine
Start: 2026-05-14End: 2027-10-01Target: 50Updated: 2026-06-10

Phase 3

The Prevention of Delirium and Complications Associated With Surgical Treatments Multi Center Clinical Trial
CompletedNCT01690988
Washington University School of MedicineDelirium
Start: 2014-02-01End: 2017-07-31Updated: 2018-06-06
Effect of Different Anesthetic Drugs on Electrocorticography (ECOG).
Active, not recruitingNCT07165262
Children's Cancer Hospital Egypt 57357Brain Tumor, Epilepsy
Start: 2025-08-18End: 2027-03-31Updated: 2025-09-10

Phase 4

Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial
Not yet recruitingNCT07214701
Assiut UniversityVaricocelectomy
Start: 2025-11-01End: 2026-12-01Target: 58Updated: 2025-10-09

Unknown Phase

Induction Agents in ECT: Effects on Seizure Duration, Quality, and Recovery
CompletedNCT07596095
Dr. Lutfi Kirdar Kartal Training and Research HospitalAnesthesia, General, Electroconvulsive Therapy
Start: 2024-07-17End: 2025-12-31Updated: 2026-05-19

Related Papers

Perioperative Epidural Use and Risk of Delirium in Surgical Patients: A Secondary Analysis of the PODCAST Trial
Anesthesia & Analgesia2019-03-0218 citations
Intraoperative ketamine for prevention of depressive symptoms after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial.
2018-09-1952 citations
Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial.
2017-05-30322 citations
The Prevention of Delirium and Complications Associated with Surgical Treatments (PODCAST) study: protocol for an international multicentre randomised controlled trial
BMJ Open2014-09-0138 citations