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JNJ-56136379

DRUG13 trials

Sponsors

Janssen Sciences Ireland UC, Janssen Research & Development, LLC, Arrowhead Pharmaceuticals

Conditions

HealthyHepatic ImpairmentHepatitis BHepatitis B, ChronicHepatitis, ChronicRenal Insufficiency

Phase 1

A Study of Orally Administered JNJ-56136379 to Evaluate Safety, Tolerability and Pharmacokinetics After Single Ascending Doses and One Multiple Dose Regimen in Healthy Participants (Part I), and After Multiple Dose Regimens in Participants With Chronic Hepatitis B (Part II)
CompletedNCT02662712
Janssen Sciences Ireland UCHealthy, Hepatitis, Chronic
Start: 2015-12-17End: 2018-06-29Updated: 2025-02-03
A Study to Investigate Safety, Tolerability, and Pharmacokinetics of JNJ-56136379 in Healthy Japanese Adult Participants
CompletedNCT02933580
Janssen Research & Development, LLCHealthy
Start: 2016-10-12End: 2017-02-04Updated: 2018-03-16
A Study in Healthy Female Participants to Investigate the Effect of JNJ-56136379 at Steady-state on the Single-dose Pharmacokinetics of Ethinylestradiol and Drospirenone (Oral Contraceptive) and on the Single-dose Pharmacokinetics of Midazolam (Probe Substrate for Cytochrome P450 3A4)
CompletedNCT03111511
Janssen Sciences Ireland UCHealthy
Start: 2017-03-27End: 2017-08-23Updated: 2017-09-06
Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)
CompletedNCT03365947
Arrowhead PharmaceuticalsHepatitis B
Start: 2018-03-27End: 2020-04-23Updated: 2025-10-22
A Study to Evaluate the Effect of Itraconazole on JNJ-56136379 in Healthy Adult Participants
CompletedNCT03945539
Janssen Sciences Ireland UCHealthy
Start: 2019-05-15End: 2019-10-04Updated: 2025-02-03
A Study to Evaluate the Effect of Hepatic Impairment on JNJ-56136379
CompletedNCT04208399
Janssen Sciences Ireland UCHepatic Impairment
Start: 2020-01-09End: 2021-03-26Updated: 2021-04-20
A Study to Evaluate the Effect of Renal Impairment on JNJ-56136379 in Adult Participants
TerminatedNCT04474210
Janssen Research & Development, LLCRenal Insufficiency
Start: 2020-08-19End: 2020-11-30Updated: 2021-07-23
A Study of JNJ-56136379 in Healthy Participants
WithdrawnNCT04853524
Janssen Research & Development, LLCHealthy
Start: 2021-05-06End: 2021-07-30Updated: 2021-07-15

Phase 2

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