Jakavi 15 mg tablets
Sponsors
Karyopharm Therapeutics Inc., Incyte Corp., Assistance Publique Hopitaux De Paris, Bristol-Myers Squibb Services Unlimited Company, Ryvu Therapeutics S.A.
Conditions
DIPSS-Intermediate or High Risk MyelofibrosisInclusion body MyositisMyelofibrosisThis study is designed to accept patients with varied disease originsTreatment naïve patients with MFdepending on the parent protocolhaemophagocytic lymphohistiocytosis (HLH) in children
Phase 1
Phase 2
An Open-Label, Multicenter, Rollover Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib
RecruitingCTIS2023-507225-42-00
Start: 2024-11-05Target: 6Updated: 2025-08-05
An Open-Label Clinical Trial of RVU120 as Monotherapy and in Combination with Ruxolitinib in Patients with Intermediate or High-Risk, Primary or Secondary Myelofibrosis (POTAMI-61)
RecruitingCTIS2024-511688-27-00
Start: 2024-09-19Target: 83Updated: 2025-12-16
BIGTIM: Blocking Interferon-γ by ruxolitinib for Treating Inclusion body Myositis: a phase IIb trial.
RecruitingCTIS2023-507666-32-00
Start: 2025-05-27Target: 80Updated: 2025-08-28
R-HLH - Efficacy of Ruxolitinib as first line treatment in primary haemophagocytic lymphohistiocytosis (HLH) in children: a Phase 2, multicentre, non-comparative study
RecruitingCTIS2024-516105-23-01
Start: 2024-11-10Target: 20Updated: 2024-12-16