Itraconazole (ITZ)

DRUG6 trials

Sponsors

AbbVie, Alexandria University, Multan Medical And Dental College, Post Graduate Institute of Medical Education and Research, Chandigarh

Conditions

Biliary Tract CancersChronic Pulmonary AspergillosisDermatophytosisEsophageal Squamous Cell CarcinomaHead and Neck Squamous-Cell CarcinomaHealthy VolunteerHepatocellular CarcinomaHormone Receptor+/Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer

Phase 1

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

RecruitingNCT06084481

AbbVieBiliary Tract Cancers, Esophageal Squamous Cell Carcinoma, Head and Neck Squamous-Cell Carcinoma +5

Start: 2023-11-09End: 2027-09-01Target: 325Updated: 2026-10-14

A Study to Assess Multiple Ascending Dose, Drug-Drug Interaction, and Asian Pharmacokinetic Study of ABBV-1088

TerminatedNCT06579300

AbbVieHealthy Volunteer

Start: 2024-09-04End: 2025-09-03Updated: 2025-10-30

A Study to Assess Change in How Oral Icalcaprant With Itraconazole Moves Through the Body in Healthy Adult Participants

CompletedNCT06722430

AbbVieHealthy Volunteer

Start: 2024-11-13End: 2025-01-13Updated: 2025-01-28

Phase 3

A Study of Itraconazole and Posaconazole for Chronic Pulmonary Aspergillosis

Not yet recruitingNCT07825259

Post Graduate Institute of Medical Education and Research, ChandigarhChronic Pulmonary Aspergillosis

Start: 2026-11-01End: 2029-12-31Target: 220Updated: 2026-10-01

Unknown Phase

Comparison Between Continuous and Pulse Itraconazole in Tinea Capitis in Children

RecruitingNCT07184203

Alexandria UniversityTinea Capitis

Start: 2025-03-09End: 2025-12-31Target: 120Updated: 2025-09-19

Comparison of Combination of Itraconazole and Isotretinoin Versus Itraconazole Alone in the Treatment of Resistant Trichophyton Infection

CompletedNCT07420894

Multan Medical And Dental CollegeDermatophytosis, Resistant Dermatophyte Infection, Trichophyton Infection

Start: 2025-01-29End: 2025-07-28Updated: 2026-02-19

Related Papers

Phase 1 basket study of telisotuzumab adizutecan (Temab-A, ABBV-400), a c-Met protein–targeting antibody-drug conjugate: Results from patients with head and neck squamous cell carcinoma (HNSCC).

Journal of Clinical Oncology2026-05-27

Phase 1 basket study of telisotuzumab adizutecan (Temab-A, ABBV-400), a c-Met protein–targeting antibody-drug conjugate: Results from patients with platinum-resistant ovarian/primary peritoneal/fallopian tube cancer (PROC).

Journal of Clinical Oncology2026-05-27

Phase 1b study evaluating the efficacy and safety of ABBV-400, a c-Met–targeting antibody-drug conjugate, in select advanced solid tumor indications.

Journal of Clinical Oncology2024-06-01