ITMHA

COMBINATION_PRODUCT2 trials

Sponsors

St. Jude Children's Research Hospital

Conditions

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaMyelodysplastic Syndromes

Phase 1

Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) I

Active, not recruitingNCT02553460

St. Jude Children's Research HospitalAcute Lymphoblastic Leukemia

Start: 2016-01-29End: 2031-10-31Updated: 2025-12-10

Phase 2

A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

Active, not recruitingNCT03164057

St. Jude Children's Research HospitalAcute Myeloid Leukemia, Myelodysplastic Syndromes

Start: 2017-06-15End: 2027-06-01Updated: 2026-01-28

Related Papers

Epigenetic priming improves survival for pediatric Acute Myeloid Leukemia: Results from the multicenter randomized AML16 trial

Blood2025-11-03

Pediatric acute myeloid leukemia with breast chloromas

eJHaem2023-03-151 citations

Proteomic Analysis Identifies Epigenetic Modifiers and Potential Negative Regulators of Leukemogenesis KMD6A and SETDB1 to be Induced Post <i>In Vivo</i> Decitabine Exposure in Pediatric AML

Blood2022-11-15

KMT2A-Rearranged Infant Acute Lymphoblastic Leukemia Cells Undergo ER-Stress-Induced Apoptosis Following Exposure to Proteasome Inhibitors

Blood2019-11-131 citations

Epigenetic Regulation of OCTN1‐mediated Cytarabine Transport in Acute Myeloid Leukemia

The FASEB Journal2019-04-01