Isradipine

DRUG7 trials

Conditions

Bipolar DisorderChronic Spinal Cord InjuryCravingDrug DependenceNicotine DependenceOpioid DependenceParkinson DiseaseSchizoaffective Disorder

Early Phase 1

Isradipine Enhancement of Virtual Reality Cue Exposure for Smoking Cessation

CompletedNCT03083353

University of Texas at AustinCraving, Nicotine Dependence, Smoking Behaviors +3

Start: 2020-01-22End: 2023-06-14Updated: 2025-06-15

Phase 1

Drug Discrimination in Methadone-Maintained Humans Study 1

CompletedNCT00593463

University of ArkansasDrug Dependence

Start: 2006-09-30End: 2010-05-31Target: 40Updated: 2011-03-11

Improving Buprenorphine Detoxification Outcomes With Isradipine

CompletedNCT01895270

University of ArkansasOpioid Dependence

Start: 2013-10-31End: 2016-04-30Updated: 2017-06-05

Phase 2

Adjunctive Isradipine for the Treatment of Bipolar Depression

TerminatedNCT01784666

Massachusetts General HospitalBipolar Disorder

Start: 2013-02-28End: 2014-04-30Updated: 2017-04-20

Phase 3

Efficacy of Isradipine in Early Parkinson Disease

CompletedNCT02168842

University of RochesterParkinson Disease

Start: 2014-11-30End: 2018-11-30Updated: 2020-01-14

Unknown Phase

Evaluating Isradipine for Cognitive Enhancement in Schizophrenia and Schizoaffective Disorder

CompletedNCT01658150

Icahn School of Medicine at Mount SinaiSchizoaffective Disorder, Schizophrenia

Start: 2012-09-30End: 2018-01-02Updated: 2018-12-05

Impact of Persistent Conductances on Motor Unit Firing in SCI

NCT02136823

Shirley Ryan AbilityLabChronic Spinal Cord Injury

Start: 2009-06-30Target: 50Updated: 2014-05-13

JMIR Research Protocols2025-07-07

Improving Prediction of Falls and Cognitive Impairment in Parkinson Disease: Protocol for a Decentralized Observational Study (Preprint)

2025-02-03

Isradipine augmentation of virtual reality cue exposure therapy for tobacco craving: a triple-blind randomized controlled trial.

2024-05-241 citations

Calcium handling: a strategy to fight neurodegeneration in Alzheimer’s disease

Neural Regeneration Research2023-04-131 citations

Enrollment of Participants From Marginalized Racial and Ethnic Groups

Neurology Clinical Practice2023-01-1814 citations

Isradipine plasma pharmacokinetics and exposure–response in early Parkinson’s disease

Annals of Clinical and Translational Neurology2021-01-1847 citations

Isradipine Versus Placebo in Early Parkinson Disease: A Randomized Trial.

2020-03-31141 citations

Feasibility and Preliminary Efficacy of Isradipine During Outpatient Buprenorphine Stabilization and Detoxification: A Pilot Randomized, Placebo-Controlled Trial

Substance Abuse Research and Treatment2020-01-012 citations