Isoquercetin

DRUG9 trials

Conditions

COVID-19Cardiovascular DiseaseChronic Kidney DiseaseCoronavirus Disease 2019Covid19Epithelial Ovarian CancerKidney CancerOvarian Cancer

Phase 1

Isoquercetin as an Adjunct Therapy in Patients With Kidney Cancer Receiving First-line Sunitinib: a Phase I/II Trial

NCT02446795

Consorzio OncotechKidney Cancer, Renal Cell Carcinoma

Start: 2016-11-30End: 2017-12-31Target: 104Updated: 2017-01-18

Phase 2

Cancer Associated Thrombosis and Isoquercetin (CATIQ)

CompletedNCT02195232

Jeffrey Zwicker, MDThromboembolism of Vein in Non-small Cell Lung Cancer, Thromboembolism of Vein in Pancreatic Cancer, Thromboembolism of Vein VTE in Colorectal Cancer

Start: 2015-01-31End: 2019-10-22Updated: 2021-03-03

Nitrite, Isoquercetin and Endothelial Dysfunction (NICE) Trial

CompletedNCT02552888

Tulane UniversityChronic Kidney Disease

Start: 2016-03-31End: 2017-06-30Updated: 2021-04-20

Isoquercetin in Sickle Cell Anemia

WithdrawnNCT04474626

Jeffrey Zwicker, MDSickle Cell-Beta0-Thalassemia, Sickle Cell Disease

Start: 2020-12-31End: 2024-12-31Updated: 2021-01-11

Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects With Stable Sickle Cell Disease

CompletedNCT04514510

National Heart, Lung, and Blood Institute (NHLBI)Sickle Cell Disease

Start: 2020-11-02End: 2022-07-07Updated: 2024-01-02

Masitinib Combined With Isoquercetin and Best Supportive Care in Hospitalized Patients With Moderate and Severe COVID-19

NCT04622865

AB ScienceCoronavirus Disease 2019, COVID-19, SARS-CoV 2

Start: 2020-06-01End: 2023-12-31Target: 200Updated: 2023-02-06

Study to Investigate the Clinical Efficacy of Isoquercetin in Patients With COVID-19

NCT04733651

Nepal Health Research CouncilCovid19

Start: 2021-02-20End: 2021-08-15Target: 250Updated: 2021-02-05

A Study of Isoquercetin in People With Ovarian Cancer

RecruitingNCT07303894

Memorial Sloan Kettering Cancer CenterEpithelial Ovarian Cancer, Ovarian Cancer, Serous Ovarian Tumor

Start: 2026-01-22End: 2032-01-01Target: 90Updated: 2026-09-15

Unknown Phase

Impact of isoQUercetin and Aspirin on Platelet Function

WithdrawnNCT02866448

University of ReadingCardiovascular Disease

Start: 2016-08-31End: 2016-10-31Updated: 2016-11-29

Blood Advances2023-12-2910 citations

MasitinibL shows promise as a drug-like analog of masitinib that elicits comparable SARS-Cov-2 3CLpro inhibition with low kinase preference

Scientific Reports2023-04-2815 citations

Effects of Isoquercetin on Plasma Protein Disulfide Isomerase Activity and Extracellular Vesicle Tissue Factor Antigen/Activity in Sickle Cell Disease

Blood2022-11-15

Combination Treatment with Sodium Nitrite and Isoquercetin on Endothelial Dysfunction among Patients with CKD

Clinical Journal of the American Society of Nephrology2020-10-0614 citations

Targeting protein disulfide isomerase with the flavonoid isoquercetin to improve hypercoagulability in advanced cancer.

2019-02-21119 citations

Targeting Protein Disulfide Isomerase with the Oral Flavonoid Isoquercetin Prevents Venous Thromboembolism in Advanced Cancer: Results of a Multi-Dose, Multi-Center, Phase II Clinical Trial (CATIQ Study)

Blood2018-11-291 citations

Isoquercetin

Sponsors

Conditions

Phase 1

Phase 2

Unknown Phase

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