ISF35

BIOLOGICAL5 trials

Sponsors

Memgen, LLC, Januario Castro, M.D.

Conditions

Chronic Lymphocytic LeukemiaDiffuse Large Cell LymphomaFollicular LymphomaMantle Cell LymphomaNon-Hodgkin's LymphomaSmall Lymphocytic Lymphoma

Phase 1

A Phase Ib Study of ISF35 in Combination With Chemotherapy (FCR) in Subjects With Relapsed, Refractory, and/or 17p- CLL

CompletedNCT00772486

Memgen, LLCChronic Lymphocytic Leukemia

Start: 2008-09-30End: 2013-04-30Updated: 2021-09-22

A Phase I Trial of Autologous CLL B Cells Transduced to Express Chimeric CD154 (ISF35)

CompletedNCT00779883

Memgen, LLCChronic Lymphocytic Leukemia

Start: 2006-06-30End: 2008-03-31Updated: 2008-10-24

A Phase I Extension Trial of Repeated Infusions of ISF35

CompletedNCT00783588

Memgen, LLCChronic Lymphocytic Leukemia

Start: 2007-05-31End: 2008-09-30Updated: 2008-10-31

Phase 2

Study of Repeat Intranodal Injection of Memgen's Cancer Vaccine, Ad-ISF35, in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

TerminatedNCT00849524

Januario Castro, M.D.Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma

Start: 2009-01-31End: 2014-07-31Updated: 2015-12-30

Study of Repeat Intranodal Injections of Ad-ISF35

TerminatedNCT00942409

Januario Castro, M.D.Chronic Lymphocytic Leukemia, Diffuse Large Cell Lymphoma, Follicular Lymphoma +3

Start: 2009-06-30End: 2014-07-31Updated: 2015-12-30