irofulven

DRUG17 trials

Sponsors

National Cancer Institute (NCI), Memorial Sloan Kettering Cancer Center, The University of Texas Health Science Center at San Antonio, University of Chicago, Gynecologic Oncology Group

Conditions

Brain and Central Nervous System TumorsBreast CancerCervical CancerColorectal CancerEndometrial CancerFallopian Tube CancerGastric CancerKidney Cancer

Phase 1

Chemotherapy in Treating Patients With Progressive or Recurrent Brain Tumors

CompletedNCT00012038

New Approaches to Brain Tumor Therapy ConsortiumBrain and Central Nervous System Tumors

Start: 2001-07-31End: 2003-10-31Updated: 2013-06-24

Irofulven in Treating Children With Recurrent or Refractory Solid Tumors

CompletedNCT00003370

National Cancer Institute (NCI)Unspecified Childhood Solid Tumor, Protocol Specific

Start: 1998-08-31Updated: 2013-02-05

6-Hydroxymethylacylfulvene in Treating Patients With Refractory Myelodysplastic Syndrome, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Blastic Phase Chronic Myelogenous Leukemia

CompletedNCT00003997

National Cancer Institute (NCI)Leukemia, Myelodysplastic Syndromes

Start: 1999-07-31Updated: 2013-02-08

Study of Irofulven in Combination With Oxaliplatin in Patients With Advanced Solid Tumors

CompletedNCT00374660

Eisai Inc.Liver Cancer

Start: 2003-06-30End: 2007-04-30Updated: 2021-12-08

Phase 2

Irofulven in Treating Patients With Metastatic Breast Cancer

CompletedNCT00003796

National Cancer Institute (NCI)Breast Cancer

Start: 1999-05-31Updated: 2013-02-11

Irofulven in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cancer

CompletedNCT00053365

National Cancer Institute (NCI)Primary Peritoneal Cavity Cancer, Recurrent Ovarian Epithelial Cancer

Start: 2003-06-30End: 2010-07-31Updated: 2019-07-24

Irofulven in Treating Patients With Recurrent or Metastatic Gastric Cancer

CompletedNCT00062257

Cancer Therapeutics Research GroupGastric Cancer

Start: 2003-06-30End: 2006-09-30Updated: 2013-05-15

Irofulven in Treating Patients With Persistent or Recurrent, Refractory Endometrial Cancer

CompletedNCT00005031

Gynecologic Oncology GroupEndometrial Cancer

Start: 2000-08-31Updated: 2013-05-27

Irofulven in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, or Peritoneal Cancer

CompletedNCT00019552

National Cancer Institute (NCI)Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer

Start: 1998-09-30End: 2004-04-30Updated: 2013-06-20

Irofulven in Treating Patients With Stage IV Melanoma

CompletedNCT00005968

University of Colorado, DenverMelanoma (Skin)

Start: 1999-11-30End: 2002-12-31Updated: 2013-05-30

Irofulvene in Treating Patients With Stage III or Stage IV Pancreatic Cancer

CompletedNCT00003760

The University of Texas Health Science Center at San AntonioPancreatic Cancer

Start: 1998-11-30End: 2000-05-31Updated: 2012-08-09

Irofulven in Treating Patients With Metastatic or Recurrent Colorectal Cancer

WithdrawnNCT00003786

University of ChicagoColorectal Cancer

Start: 1999-04-30End: 2000-11-30Updated: 2014-03-07

Irofulven in Treating Patients With Stage IVB or Recurrent Cervical Cancer

CompletedNCT00005070

Memorial Sloan Kettering Cancer CenterCervical Cancer

Start: 2000-01-31End: 2001-05-31Updated: 2013-06-19

6-Hydroxymethylacylfulvene in Treating Patients With Metastatic Kidney Cancer

CompletedNCT00003390

Memorial Sloan Kettering Cancer CenterKidney Cancer

Start: 1998-06-30End: 2004-08-31Updated: 2013-06-21

Study of Irofulven in Patients With Hormone-refractory Prostate Cancer

CompletedNCT00124566

Eisai Inc.Prostate Cancer

Start: 2004-06-30End: 2009-12-31Updated: 2016-01-18

Irofulven in AR-targeted and Docetaxel-Pretreated mCRPC Patients With Drug Response Predictor (DRP®)

CompletedNCT03643107

Allarity TherapeuticsMetastatic Castration-Resistant Prostate Cancer Patients

Start: 2018-10-17End: 2022-08-01Updated: 2025-01-23

Phase 3

Irofulven Compared With Fluorouracil in Treating Patients With Pancreatic Cancer

CompletedNCT00033735

Eisai Inc.Pancreatic Cancer

Start: 2000-01-31Updated: 2012-12-24