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Irinotecan Hydrochloride 20 mg/ml concentrate for solution for infusion

DRUG6 trials

Sponsors

Vastra Gotalandsregionen, Pfizer Inc., Institut Gustave Roussy, Catharina Ziekenhuis Stichting, Scandion Oncology A/S

Conditions

Advanced pancreatic cancerColorectal CancerColorectal cancer (BRAF V600E-mutant mCRC)Irresectable peritoneal metastases of colorectal cancerMetastatic Colorectal CancerPatients with High Risk Neuroblastoma

Phase 2

Phase 3

Standard versus Prolonged Neoadjuvant (Conversion) Chemotherapy to prolong survival of patients with Borderline and Locally Advanced Pancreatic Cancer: a phase III randomized controlled trial; ADVANTAGE
RecruitingCTIS2022-502117-29-00
Vastra GotalandsregionenAdvanced pancreatic cancer
Start: 2023-10-19Target: 754Updated: 2025-12-15
C4221015 - AN OPEN-LABEL, MULTICENTER, RANDOMIZED PHASE 3 STUDY OF FIRST LINE ENCORAFENIB PLUS CETUXIMAB WITH OR WITHOUT CHEMOTHERAPY VERSUS STANDARD OF CARE THERAPY WITH A SAFETY LEAD-IN OF ENCORAFENIB AND CETUXIMAB PLUS CHEMOTHERAPY IN PARTICIPANTS WITH METASTATIC BRAF V600E MUTANT COLORECTAL CANCER
Active, not recruitingCTIS2023-509405-77-00
Pfizer Inc.Colorectal cancer (BRAF V600E-mutant mCRC)
Start: 2021-02-16Target: 300Updated: 2026-01-26
High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN) “Randomized, international and multicentric phase 3 study that evaluates and compares 2 treatment strategies in 3 therapeutic phases (induction, high-dose chemotherapy and radiotherapy) for patients with high-risk neuroblastoma and introduces chemoimmunotherapy for patients with insufficient metastatic response after induction chemotherapy
RecruitingCTIS2024-514917-36-00
Institut Gustave RoussyPatients with High Risk Neuroblastoma
Start: 2024-11-21Target: 719Updated: 2025-01-17
A Randomized, Open-label, Phase 3 Trial of Petosemtamab in Combination With mFOLFOX6 or FOLFIRI Versus Cetuximab in Combination With mFOLFOX6 or FOLFIRI as First-line Treatment for Participants With RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer.
Not yet recruitingCTIS2026-525883-17-00
Genmab A/SColorectal Cancer
Target: 159Updated: 2026-10-20