Irinotecan Hydrochloride 20 mg/ml concentrate for solution for infusion
Sponsors
Vastra Gotalandsregionen, Pfizer Inc., Institut Gustave Roussy, Catharina Ziekenhuis Stichting, Scandion Oncology A/S
Conditions
Advanced pancreatic cancerColorectal cancer (BRAF V600E-mutant mCRC)Irresectable peritoneal metastases of colorectal cancerMetastatic Colorectal CancerPatients with High Risk Neuroblastoma
Phase 2
Intraperitoneal irinotecan with concomitant FOLFOX and bevacizumab for patients with unresectable colorectal peritoneal metastases – a phase II study
Not yet recruitingCTIS2024-517152-34-00
Target: 85Updated: 2024-09-03
An open-label phase II prospective clinical trial to investigate safety, tolerability, maximum tolerated dose and anti-tumor effect for SCO-101 in combination with FOLFIRI as a safe and efficient treatment modality in metastatic or advanced colorectal cancer (mCRC) patients with acquired FOLFIRI resistant cancer disease
Active, not recruitingCTIS2024-518877-33-00
Start: 2022-03-17Target: 31Updated: 2024-11-19
Phase 3
Standard versus Prolonged Neoadjuvant (Conversion) Chemotherapy to prolong survival of patients with Borderline and Locally Advanced Pancreatic Cancer: a phase III randomized controlled trial; ADVANTAGE
RecruitingCTIS2022-502117-29-00
Start: 2023-10-19Target: 754Updated: 2025-12-15
C4221015 - AN OPEN-LABEL, MULTICENTER, RANDOMIZED PHASE 3 STUDY OF FIRST LINE ENCORAFENIB PLUS CETUXIMAB WITH OR WITHOUT CHEMOTHERAPY
VERSUS STANDARD OF CARE THERAPY WITH A SAFETY LEAD-IN OF ENCORAFENIB AND CETUXIMAB PLUS CHEMOTHERAPY IN PARTICIPANTS WITH METASTATIC BRAF V600E MUTANT COLORECTAL CANCER
Active, not recruitingCTIS2023-509405-77-00
Start: 2021-02-16Target: 300Updated: 2026-01-26
High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN) “Randomized, international and multicentric phase 3 study that evaluates and compares 2 treatment strategies in 3 therapeutic phases (induction, high-dose chemotherapy and radiotherapy) for patients with high-risk neuroblastoma and introduces chemoimmunotherapy for patients with insufficient metastatic response after induction chemotherapy
RecruitingCTIS2024-514917-36-00
Start: 2024-11-21Target: 719Updated: 2025-01-17