Intravitreal Aflibercept

DRUG5 trials

Sponsors

Fondation Ophtalmologique Adolphe de Rothschild, Association for Innovation and Biomedical Research on Light and Image, Unity Health Toronto, Southeast Clinical Research Associates, LLC, Stanford University

Conditions

Age Related Macular DegenerationDiabetic Macular EdemaMacular EdemaPolypoidal Choroidal VasculopathyRetinal Vein Occlusion

Phase 2

A Pharmacokinetic stuDy of intRavitreal Aflibercept Injection in Vitrectomized and Non-vitrectomized Eyes With Diabetic Macular Edema

WithdrawnNCT04588948

Stanford UniversityDiabetic Macular Edema

Start: 2020-12-31End: 2021-12-31Updated: 2022-04-28

Phase 4

Randomized, Double-masked, Sham-controlled Phase 4 Study, Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Monotherapy Compared to Aflibercept With Adjunctive Photodynamic Therapy in Patients With Polypoidal Choroidal Vasculopathy

CompletedNCT02495181

Association for Innovation and Biomedical Research on Light and ImagePolypoidal Choroidal Vasculopathy

Start: 2015-11-23End: 2019-12-17Updated: 2020-01-10

Cytokine and Visual Outcome Variations in Eyes Receiving Aflibercept

Unity Health TorontoAge Related Macular Degeneration, Diabetic Macular Edema, Macular Edema +1

Start: 2017-02-28End: 2024-02-28Target: 168Updated: 2021-04-28

Intravitreal Alfibercept for Center Involved DME Previously Managed With Intravitreal Ranibizumab

WithdrawnNCT03059277

Southeast Clinical Research Associates, LLCDiabetic Macular Edema

Start: 2018-06-01End: 2020-09-30Updated: 2018-06-14

Unknown Phase

Assessment of Visual Acuity in Patients With Polypoidal Choroidal Vasculopathy and Aflibercept Treatment

CompletedNCT02381730

Fondation Ophtalmologique Adolphe de RothschildPolypoidal Choroidal Vasculopathy

Start: 2014-01-31End: 2017-08-31Updated: 2017-12-08

Related Papers

Efficacy and Safety of Intravitreal Aflibercept Treat and Extend for Polypoidal Choroidal Vasculopathy in the ATLANTIC Study: A Randomized Clinical Trial

Ophthalmologica2021-07-1311 citations

Protocol for a randomised, double-masked, sham-controlled phase 4 study on the efficacy, safety and tolerability of intravitreal aflibercept monotherapy compared with aflibercept with adjunctive photodynamic therapy in polypoidal choroidal vasculopathy: the ATLANTIC study

BMJ Open2017-08-017 citations