Intrathecal triple therapy (methotrexate + hydrocortisone + cytarabine)

DRUG2 trials

Sponsors

St. Jude Children's Research Hospital

Conditions

Acute Lymphoblastic LeukemiaLymphoblastic LymphomaMixed Phenotype Acute LeukemiaT-cell Acute Lymphoblastic LeukemiaT-cell Lymphoma

Phase 2

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

RecruitingNCT06390319

St. Jude Children's Research HospitalMixed Phenotype Acute Leukemia, T-cell Acute Lymphoblastic Leukemia, T-cell Lymphoma

Start: 2024-12-27End: 2033-12-01Target: 100Updated: 2026-02-27

Phase 4

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

RecruitingNCT06289673

St. Jude Children's Research HospitalAcute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Mixed Phenotype Acute Leukemia

Start: 2024-12-26End: 2039-05-01Target: 850Updated: 2026-03-03