intraperitoneal chemotherapy

DRUG8 trials

Sponsors

Kodera Yasuhiro, City of Hope Medical Center, Far Eastern Memorial Hospital, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Instituto do Cancer do Estado de São Paulo

Conditions

Advanced Ovarian CancerClinical Stage IV Gastric Cancer AJCC v8Clinical Stage IVA Gastric Cancer AJCC v8Clinical Stage IVB Gastric Cancer AJCC v8Gastric CancerGastric cancer Gastric cancer, peritoneal metastasisMalignant Uterine NeoplasmMetastatic Appendix Carcinoma

Phase 1

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

RecruitingNCT04329494

City of Hope Medical CenterClinical Stage IVA Gastric Cancer AJCC v8, Clinical Stage IVB Gastric Cancer AJCC v8, Clinical Stage IV Gastric Cancer AJCC v8 +24

Start: 2020-08-21End: 2028-01-05Target: 49Updated: 2026-08-26

Phase 2

Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a multicentre, open-label, single-arm, phase II study (CRC-PIPAC)

Active, not recruitingNL-OMON49271

Catharina-ziekenhuisUnresectable isolated colorectal peritoneal metastases

Start: 2017-10-10Target: 20Updated: 2024-02-28

Phase II study of intraperitoneal paclitaxel combined with S-1 plus cisplatin for advanced gastric cancer with peritoneal metastasis

Active, not recruitingJPRN-jRCTs041180079

Kodera YasuhiroGastric cancer Gastric cancer, peritoneal metastasis

Start: 2017-04-14Target: 50Updated: 2026-06-29

Intraperitoneal Chemotherapy Guided by the Detection of DNA in Peritoneal Lavage Fluid in Patients With Gastric Cancer

Cancer Institute and Hospital, Chinese Academy of Medical SciencesGastric Cancer

Start: 2022-06-28End: 2024-06-20Target: 68Updated: 2022-08-11

Intraperitoneal Chemotherapy in Gastric Cancer With Peritoneal Carcinomatosis

Instituto do Cancer do Estado de São PauloGastric Cancer, Peritoneal Carcinomatosis

Start: 2022-06-01End: 2025-01-31Target: 30Updated: 2023-03-23

INTERACT Stomach-II

RecruitingNCT07133490

Erasmus Medical CenterPeritoneal Metastases From Gastric Cancer

Start: 2025-10-01End: 2028-07-01Target: 55Updated: 2026-06-01

Unknown Phase

Palliative Care During Intraperitoneal Chemotherapy in Patients With Ovarian Cancer

CompletedNCT00804258

City of Hope Medical CenterOvarian Cancer

Start: 2007-08-31End: 2012-01-31Updated: 2015-11-06

Dose-dense Chemotherapy Versus Intraperitoneal Chemotherapy as First-line Chemotherapy in Advanced Ovarian Cancer

CompletedNCT04135521

Far Eastern Memorial HospitalAdvanced Ovarian Cancer

Start: 2019-10-28End: 2020-03-31Updated: 2020-06-29

Related Papers

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Pleura and Peritoneum2025-12-21

Safety and Efficacy of Cisplatin and Doxorubicin Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Patients with Ovarian Cancer with Peritoneal Metastases: A Multicenter US Phase I Trial

Annals of Surgical Oncology2025-09-302 citations

Pressurized intraperitoneal aerosolized chemotherapy (PIPAC) experience in patients with recurrent low grade serous ovarian carcinoma (LGSOC): sub-cohort report of phase 1 clinical trial

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Safety and Efficacy of Oxaliplatin Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Colorectal and Appendiceal Cancer with Peritoneal Metastases: Results of a Multicenter Phase I Trial in the USA.

2023-07-2720 citations

Safety and efficacy of PIPAC in patients with ovarian cancer with peritoneal metastases: A first-in-US phase I study.

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EP334/#194 Single cell transcriptomic analysis of a low grade serous ovarian cancer patient treated with pressurized intraperitoneal aerosolized chemotherapy (PIPAC)

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Safety and efficacy of pressurized intraperitoneal aerosolized chemotherapy in appendiceal and colorectal cancer patients with peritoneal carcinomatosis: A first-in-US phase I study.

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A Unique Technique to Treat Peritoneal Carcinomatosis

Oncology Times2020-10-29