Intraocular pressure (IOP) is dependent on the balance between the production of aqueous fluid within the eye and the rate at which aqueous leaves the eye through the trabecular meshwork (TM) in the angle of the eye’s anterior chamber. The medication Ibopamine (Trazyl: Pharmainvest SpA, Milano, Italy) which is a dopamine receptor agonist, will temporarily increase aqueous production and dilate the pupil. A healthy eye with healthy TM cells will overcome this increase, pump aqueous out of the eye
Sponsors
John Landers
Phase 4
The Predicting Glaucoma Progression Project
CompletedACTRN12611001191987
Start: 2012-07-02End: 2013-07-29Target: 40Updated: 2020-01-13
The Predicting Glaucoma Development Project: Examining the utility of an Ibopamine challenge test to predict glaucoma development in glaucoma suspects.
Not yet recruitingACTRN12615000767505
Start: 2015-09-01Target: 100Updated: 2020-01-13