Intradiscal rhGDF-5

DRUG4 trials

Sponsors

DePuy Spine

Conditions

Degenerative Disc DiseaseEarly Lumbar Disc Degeneration

Phase 1

Intradiscal rhGDF-5 Phase I/II Clinical Trial

CompletedNCT00813813

DePuy SpineDegenerative Disc Disease

Start: 2008-06-30End: 2013-06-30Updated: 2016-02-26

A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal rhGDF-5 for the Treatment of Early Stage Lumbar Disc Degeneration

CompletedNCT01158924

DePuy SpineEarly Lumbar Disc Degeneration

Start: 2010-03-31End: 2014-03-31Updated: 2016-02-26

A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal rhGDF-5 for the Treatment of Early Stage Lumbar Disc Degeneration

CompletedNCT01182337

DePuy SpineEarly Lumbar Disc Degeneration

Start: 2010-06-30End: 2014-06-30Updated: 2016-02-26

Phase 2

A Multicenter, Randomized, Double-blind, Placebo Controlled, Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of 2 Doses of Intradiscal rhGDF-5 (Single Administration) for the Treatment of Early Stage Lumbar Disc Degeneration

CompletedNCT01124006

DePuy SpineDegenerative Disc Disease

Start: 2010-01-31End: 2014-09-30Updated: 2016-02-24