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Intra-arterial Thrombolysis

PROCEDURE5 trials

Sponsors

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, The Second Hospital of Anhui Medical University, Xiang Luo, Southwest Hospital, China, The First Affiliated Hospital with Nanjing Medical University

Conditions

Acute Ischemic StrokeBrain DiseasesCentral Retinal Artery OcclusionCerebrovascular DisordersInfarctionIschemic StrokeIschemic Stroke, AcuteMedium Vessel Occlusion

Phase 2

Intra-arterial Recombinant Human Tenecteplase Tissue-type Plasminogen Activator (rhTNK-tPA) Thrombolysis for Acute Medium Vessel Occlusion
RecruitingNCT07302854
Xiang LuoAcute Ischemic Stroke, Medium Vessel Occlusion
Start: 2025-12-30End: 2028-12-01Target: 382Updated: 2026-01-21

Phase 3

Efficacy and Safety of Intra-arterial Tenecteplase in Acute Ischemic Stroke Patients With Medium Vessel Occlusion Stroke (DATE-MeVO)
Not yet recruitingNCT07469293
Southwest Hospital, ChinaAcute Ischemic Stroke
Start: 2026-03-25End: 2028-12-31Target: 488Updated: 2026-03-20
Intra-arterial Thrombolysis For Acute Ischemic Stroke With Medium Vessel Occlusion
Not yet recruitingNCT07668323
The First Affiliated Hospital with Nanjing Medical UniversityIschemic Stroke, Acute, Medium Vessel Occlusion
Start: 2026-07-01End: 2029-08-31Target: 306Updated: 2026-06-25

Unknown Phase

Safety and Efficacy After Selective Intra-arterial Thrombolysis for Central Retinal Artery Occlusion
NCT05562284
Xinhua Hospital, Shanghai Jiao Tong University School of MedicineCentral Retinal Artery Occlusion
Start: 2022-06-01End: 2024-03-31Target: 128Updated: 2022-09-30
Intra-arterial Thrombolysis for Acute Ischemic Stroke With Medium Vessel Occlusion
RecruitingNCT07185022
The Second Hospital of Anhui Medical UniversityBrain Diseases, Cerebrovascular Disorders, Infarction +5
Start: 2026-01-06End: 2030-05-01Target: 282Updated: 2026-04-16