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intra-arterial thrombectomy
PROCEDURE
2 trials
Sponsors
The University of Texas Health Science Center, Houston
, Changhai Hospital
Conditions
Alteplase
Ischemic Stroke
Large Vessel Occlusion
Stroke
Thrombectomy
Thrombosis
Phase 4
SEdation Versus General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke
Completed
NCT03263117
The University of Texas Health Science Center, Houston
Stroke
Start: 2018-07-01
End: 2023-04-22
Updated: 2025-11-26
Unknown Phase
Direct Intra-arterial Thrombectomy in Order to Revascularize AIS Patients With Large Vessel Occlusion Efficiently in Chinese Tertiary Hospitals
Completed
NCT03469206
Changhai Hospital
Alteplase, Ischemic Stroke, Large Vessel Occlusion +2
Start: 2018-02-21
End: 2019-10-26
Updated: 2019-10-29
Related Papers
Sedation vs General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke: The SEGA Randomized Clinical Trial.
2025-12-01
Asymptomatic Hemorrhagic Events and Functional Outcomes in Acute Stroke
JAMA Network Open
2025-03-28
3 citations
Impact of anesthesia modalities on functional outcome of mechanical thrombectomy in patients with acute ischemic stroke: a subgroup analysis of DIRECT-MT trial
European journal of medical research
2023-07-10
75 citations
Mild and moderate cardioembolic stroke patients may benefit more from direct mechanical thrombectomy than bridging therapy: A subgroup analysis of a randomized clinical trial (DIRECT-MT)
Frontiers in Neurology
2022-11-24
7 citations
Early diagnosis of intracranial atherosclerotic large vascular occlusion: A prediction model based on DIRECT-MT data
Frontiers in Neurology
2022-11-03
7 citations
Effect of Admission Hyperglycemia on Safety and Efficacy of Intravenous Alteplase Before Thrombectomy in Ischemic Stroke: Post-hoc Analysis of the DIRECT-MT trial.
2022-09-23
4 citations
Baseline blood pressure does not modify the effect of intravenous thrombolysis in successfully revascularized patients
Frontiers in Neurology
2022-09-12
2 citations
CT Hyperdense Artery Sign and the Effect of Alteplase in Endovascular Thrombectomy after Acute Stroke
Radiology
2022-07-12
22 citations
Predictors and outcome of early neurological deterioration after endovascular thrombectomy: a secondary analysis of the DIRECT-MT trial
Journal of NeuroInterventional Surgery
2022-06-10
32 citations
Association of Intravenous Alteplase, Early Reperfusion, and Clinical Outcome in Patients With Large Vessel Occlusion Stroke: Post Hoc Analysis of the Randomized DIRECT-MT Trial
Stroke
2022-03-04
28 citations
Predictors of mortality in acute ischemic stroke treated with endovascular thrombectomy despite successful reperfusion: subgroup analysis of a multicentre randomised clinical trial
BMJ Open
2022-03-01
15 citations
Patient-Reported Anxiety/Depression After Endovascular Thrombectomy: A post-hoc Analysis of Direct-MT Trial
Frontiers in Neurology
2022-02-09
3 citations
Effect of stroke etiology on endovascular thrombectomy with or without intravenous alteplase: a subgroup analysis of DIRECT-MT
Journal of NeuroInterventional Surgery
2022-01-11
5 citations
Effect of Occlusion Site on the Safety and Efficacy of Intravenous Alteplase Before Endovascular Thrombectomy: A Prespecified Subgroup Analysis of DIRECT-MT
Stroke
2021-12-17
21 citations
Clinical and Imaging Indicators of Hemorrhagic Transformation in Acute Ischemic Stroke After Endovascular Thrombectomy
Stroke
2021-12-07
82 citations
Is concurrent intravenous alteplase in patients undergoing endovascular treatment for large vessel occlusion stroke cost-effective even if the cost of alteplase is only US$1?
Journal of NeuroInterventional Surgery
2021-06-29
16 citations
MR CLEAN-NO IV: intravenous treatment followed by endovascular treatment versus direct endovascular treatment for acute ischemic stroke caused by a proximal intracranial occlusion-study protocol for a randomized clinical trial.
2021-02-15
45 citations
Impact of EMS bypass to endovascular capable hospitals: geospatial modeling analysis of the US STRATIS registry
Journal of NeuroInterventional Surgery
2020-05-08
26 citations
Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke
New England Journal of Medicine
2020-05-06
796 citations
Sedation versus general anaesthesia in endovascular therapy for anterior circulation acute ischaemic stroke: the multicentre randomised controlled AMETIS trial study protocol
BMJ Open
2019-09-01
13 citations