Intra-arterial Tenecteplase

DRUG3 trials

Sponsors

ProMedica Health System, Wake Forest University Health Sciences, Beijing Tiantan Hospital

Conditions

Acute Ischemic StrokeEndovascular TreatmentIschemic StrokeMedium Vessel OcclusionTenecteplase

Phase 2

Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy Pilot Trial

CompletedNCT05172934

ProMedica Health SystemIschemic Stroke

Start: 2022-03-15End: 2023-11-01Updated: 2025-03-21

Intra-Arterial Tenecteplase Following Endovascular Thrombectomy for Large Vessel Occlusion Stroke

Enrolling by invitationNCT06781385

Wake Forest University Health SciencesAcute Ischemic Stroke

Start: 2025-09-22End: 2026-12-31Target: 40Updated: 2025-10-08

Phase 3

Intra-arterial Tenecteplase for Acute Medium Vessel Occlusion Stroke

Not yet recruitingNCT07357987

Beijing Tiantan HospitalEndovascular Treatment, Ischemic Stroke, Medium Vessel Occlusion +1

Start: 2026-01-22End: 2027-12-31Target: 488Updated: 2026-01-22

Related Papers

Safety of Adjunctive Intraarterial Tenecteplase Following Mechanical Thrombectomy: The ALLY Pilot Trial

Stroke2025-01-0814 citations

Natural Evolution of Incomplete Reperfusion in Patients Following Endovascular Therapy After Ischemic Stroke.

2024-11-203 citations

Abstract 027: Adjunctive Intra‐Arterial Tenecteplase Following Mechanical Thrombectomy. (ALLY) Pilot Trial

Stroke Vascular and Interventional Neurology2023-11-01