Intervention 1: Intervention group will treat with LT4: these patients will receive a dose of 0.5 microgram/kg.d if they have TSH less than 1.0 mIU/liter, 0.75 microgram/kg.d for TSH between 1.0 and 2
Sponsors
Shahid Beheshti University of Medical Sciences
Conditions
Condition 1: Abortion. Condition 2: Preterm labor. Condition 3: Low birth weight. Condition 4: Intra uterine growth restriction. Condition 5: Premature rupture of membranes. Condition 6: Third trimester hemorrhage.
Spontaneous abortion
Preterm labour and delivery
Disorders related to short gestation and low birth weight, not elsewhere classified
Slow fetal growth and fetal malnutrition
Premature rupture of membranes
Placenta previa, Premature separation of placenta [abruptio placentae]Condition 1: Preterm labor. Condition 2: Abortion. Condition 3: Low birth weight. Condition 4: Intra uterine growth restriction. Condition 5: Premature rupture of membranes. Condition 6: Third trimester hemorrhage.
Preterm labour and delivery
Spontaneous abortion
Disorders related to short gestation and low birth weight, not elsewhere classified
Slow fetal growth and fetal malnutrition
Premature rupture of membranes
Placenta previa, Premature separation of placenta [abruptio placentae]
Phase 2
Assessment of the effect of Levothyroxine on pregnancy outcome of euthyroid pregnant women with positive thyroid peroxidase antibody
Active, not recruitingIRCT2013100114849N1
Start: 2013-11-22Target: 300Updated: 2018-02-22
The effect of intervention by Levothyroxine on pregnancy outcome of pregnant women with isolated hypothyroxinemia
Active, not recruitingIRCT2013121714849N4
Start: 2013-10-23Target: 60Updated: 2018-02-22