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iNO

DRUG7 trials

Sponsors

University of Colorado, Denver, Emory University, University of Oklahoma, Duke University, Bellerophon Pulse Technologies

Conditions

Acute Cerebrovascular DiseaseBronchopulmonary DysplasiaCerebrovascular DisordersHeart Transplant SurgeryLung DiseasesLung Transplant SurgeryPulmonary Arterial HypertensionPulmonary Fibrosis

Phase 1

Inhaled Nitric Oxide in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy
RecruitingNCT05871606
Wake Forest University Health SciencesAcute Cerebrovascular Disease, Cerebrovascular Disorders
Start: 2026-04-16End: 2028-12-01Target: 36Updated: 2026-04-23

Phase 2

A Dose Escalation Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis or Sarcoidosis
CompletedNCT03727451
BellerophonPulmonary Fibrosis, Pulmonary Hypertension, Sarcoidosis, Pulmonary
Start: 2019-01-30End: 2022-06-15Updated: 2022-08-10

Phase 3

Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants
CompletedNCT00006401
University of Colorado, DenverBronchopulmonary Dysplasia, Lung Diseases
Start: 2000-09-30End: 2007-10-31Target: 793Updated: 2015-10-06
Study of PAH Subjects With LTOT Use That Have Demonstrated Improved Exercise Tolerance With the Use of Inhaled Nitric
WithdrawnNCT03602781
Bellerophon Pulse TechnologiesPulmonary Arterial Hypertension
Start: 2018-08-31End: 2020-06-30Updated: 2023-02-21

Phase 4

Inhaled Selective Pulmonary Vasodilators for Advanced Heart Failure Therapies and Lung Transplantation Outcomes
CompletedNCT03081052
Duke UniversityHeart Transplant Surgery, Lung Transplant Surgery
Start: 2017-05-04End: 2021-09-05Updated: 2023-02-16

Unknown Phase

NO Need to Ventilate: A Trial of Non-invasive Inhaled Nitric Oxide in Persistent Pulmonary Hypertension of the Newborn
CompletedNCT00139217
Emory UniversityPulmonary Hypertension
Start: 2005-08-31End: 2007-09-30Target: 400Updated: 2014-05-29
Inhaled Nitric Oxide (iNO) as an Adjunct to Neonatal Resuscitation
CompletedNCT01220687
University of OklahomaRespiratory Distress Syndrome in Premature Infants, Very Low Birth Weight Baby
Start: 2011-04-30End: 2017-05-01Updated: 2020-08-19

Related Papers

Abstract 18472: Plasma Proteome Changes in Heart Failure and Non-Heart Failure Patients Undergoing Cardiac Surgery
Circulation2023-11-07
Inhaled Epoprostenol Compared With Nitric Oxide for Right Ventricular Support After Major Cardiac Surgery
Circulation2023-07-0420 citations
Abstract 11637: Myocardial Metabolic Dysregulation and Right Ventricular Outcomes After Surgery for Advanced Heart Failure
Circulation2022-11-08
Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant
JAMA Surgery2021-11-1716 citations
Abstract 11648: Bleeding in Patients Receiving Inhaled Pulmonary Vasodilators for Heart Failure Operations
Circulation2021-11-161 citations
Early inhaled nitric oxide therapy in premature newborns with respiratory failure.
2006-07-01233 citations