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Injections, Intralesional

9 trials

Sponsors

Center for Genetic Engineering and Biotechnology (CIGB), Havana., Center for Genetic Engineering and Biotechnology (CIGB), Center for Genetic Engineering and Biothecnology (CIGB), Havana., Naval Hospital of Acapulco of the Mexican Navy, Center for Genetic Engineering and Biotechnology (CIGB), in Havana

Conditions

Cervical cancer in stages IB2 and II.Cysts and benign tumors of the jawDiabetic foot ulcer, Wagner grades 1 or 2Diabetic foot ulcer.KeloidsPatients with diabetic foot ulcer (Wagner grade 1 or 2).Skin basal cell carcinoma (BCC)Skin basal cell carcinoma, Squamous cells carcinoma.

Phase 1

InCCNM -I
Active, not recruitingRPCEC00000052
Center for Genetic Engineering and Biotechnology (CIGB)Skin basal cell carcinoma, Squamous cells carcinoma.
Start: 2002-08-05Target: 21Updated: 2026-03-30
Pharmacokinetics of intralesional EGF in patients with diabetic foot ulcers.
Active, not recruitingRPCEC00000047
Center for Genetic Engineering and Biotechnology (CIGB), Havana.Diabetic foot ulcer, Wagner grades 1 or 2
Start: 2007-11-19Target: 16Updated: 2026-03-30

Phase 2

Clinical trial, phase II, to evaluate rhEGF efficacy and safety at a dose of 25 or 75 micrograms intralesionally in patients with diabetic foot ulcer (Wagner grade 1 or 2).
Active, not recruitingRPCEC00000048
Center for Genetic Engineering and Biotechnology (CIGB), Havana.Patients with diabetic foot ulcer (Wagner grade 1 or 2).
Start: 2008-10-04Target: 35Updated: 2026-03-30
CIGB-128 administration to patients with surgically-treated keloids.
RecruitingRPCEC00000062
Center for Genetic Engineering and Biotechnology (CIGB)Keloids
Start: 2003-11-13Target: 30Updated: 2026-03-30
Application of CIGB-128 in keloid patients undergoing surgical exeresis.
Active, not recruitingRPCEC00000061
Center for Genetic Engineering and Biotechnology (CIGB)Keloids
Start: 2004-04-02Target: 45Updated: 2026-03-30
InCarbacel-II
Active, not recruitingRPCEC00000066
Center for Genetic Engineering and Biotechnology (CIGB)Skin basal cell carcinoma (BCC)
Start: 2001-03-26Target: 60Updated: 2026-03-30
Treatment for maxillary cysts
Active, not recruitingRPCEC00000274
Naval Hospital of Acapulco of the Mexican NavyCysts and benign tumors of the jaw
Start: 2015-10-29Target: 30Updated: 2026-03-30

Phase 3

CITOPROT-III
Active, not recruitingRPCEC00000060
Center for Genetic Engineering and Biothecnology (CIGB), Havana.Diabetic foot ulcer.
Start: 2006-09-27Target: 147Updated: 2026-03-30
CERVICONC-II-300 study
Active, not recruitingRPCEC00000285
Center for Genetic Engineering and Biotechnology (CIGB), in HavanaCervical cancer in stages IB2 and II.
Start: 2018-10-01Target: 144Updated: 2026-03-30

Related Papers

Treatment of advanced, recurrent, resistant to previous treatments basal and squamous cell skin carcinomas with a synergistic formulation of interferons. Open, prospective study.
2009-07-3012 citations