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Inhaled Nitric Oxide (iNO)

DRUG8 trials

Sponsors

Ellen Spurrier, University of Colorado, Denver, Baylor Research Institute, Roger Alvarez, University of California, Los Angeles

Conditions

Bronchopulmonary DysplasiaCOVID-19Cardiac ArrestCardiac Surgery Associated - Acute Kidney InjuryCardiac Surgery With Cardiopulmonary BypassCongenital Heart DefectHypertension, PulmonaryHypoxemia

Phase 2

The Effects of Inhaled Nitric Oxide After Fontan Operation
CompletedNCT00945529
Ellen SpurrierCongenital Heart Defect
Start: 2008-02-29End: 2011-12-31Updated: 2023-05-19
Examining the Use of Non-Invasive Inhaled Nitric Oxide to Reduce Chronic Lung Disease in Premature Newborns
CompletedNCT00955487
University of Colorado, DenverBronchopulmonary Dysplasia
Start: 2007-01-31End: 2014-12-31Updated: 2017-06-15
Trial of Inhaled Nitric Oxide (iNO) on Ischemia / Reperfusion Injury During Orthotopic Liver Transplantation With Marginal Grafts
CompletedNCT01172691
Baylor Research InstituteLiver Transplant
Start: 2010-07-01End: 2014-01-22Updated: 2026-01-28
iNOPulse for COVID-19
WithdrawnNCT04398290
Roger AlvarezCOVID-19, Hypoxemia, Hypoxemic Respiratory Failure
Start: 2020-12-01End: 2021-07-15Updated: 2020-08-19
Effect of iNO in Patients With Submassive and Massive PE
WithdrawnNCT04996667
University of California, Los AngelesPulmonary Embolism, Pulmonary Embolism Subacute Massive
Start: 2026-06-01End: 2028-06-30Updated: 2026-03-18
Inhaled Nitric Oxide for Cardiac Arrest in Pediatrics and Adults (iNOCAPA)
RecruitingNCT05868109
The Hospital for Sick ChildrenCardiac Arrest
Start: 2022-08-31End: 2026-01-31Target: 40Updated: 2023-11-30

Unknown Phase

Early Feasibility Study Evaluating the 3P-100 Device in Subjects With PH-ILD
Active, not recruitingNCT05867914
Third Pole Therapeutics, Inc.Hypertension, Pulmonary, Lung Diseases, Interstitial
Start: 2023-12-04End: 2024-03-29Target: 5Updated: 2024-02-14
Inhaled Nitric Oxide for Prevention of Postoperative AKI in High-Risk Cardiac Surgery Patients
Not yet recruitingNCT07544147
Shanghai Zhongshan HospitalCardiac Surgery Associated - Acute Kidney Injury, Cardiac Surgery With Cardiopulmonary Bypass
Start: 2026-04-30End: 2028-12-31Target: 330Updated: 2026-04-22