Influenza Virus Quadrivalent Inactivated Vaccine

BIOLOGICAL5 trials

Sponsors

National Institute of Allergy and Infectious Diseases (NIAID)

Conditions

Avian InfluenzaInfluenzaInfluenza Immunisation

Phase 1

Flublok or Fluzone With Advax-CpG55.2 or AF03

CompletedNCT03945825

National Institute of Allergy and Infectious Diseases (NIAID)Influenza, Influenza Immunisation

Start: 2019-06-10End: 2020-09-18Updated: 2025-10-14

A Study to Evaluate the Safety and Immunogenicity of a Single Dose of H1ssF-3928 mRNA-LNP in Healthy Adults

CompletedNCT05755620

National Institute of Allergy and Infectious Diseases (NIAID)Influenza

Start: 2023-04-05End: 2025-10-03Updated: 2025-10-31

Phase 2

Co-Administration of AS03 Adjuvanted A/H7N9 IIV With IIV4

CompletedNCT03318315

National Institute of Allergy and Infectious Diseases (NIAID)Avian Influenza, Influenza, Influenza Immunisation

Start: 2018-02-20End: 2019-07-25Updated: 2020-08-06

Phase 4

Age and Response to Flu Vaccines

CompletedNCT03328325

National Institute of Allergy and Infectious Diseases (NIAID)Influenza, Influenza Immunisation

Start: 2017-12-14End: 2020-04-20Updated: 2021-05-24

Development of Childhood Anti-Influenza Immunity

CompletedNCT03673345

National Institute of Allergy and Infectious Diseases (NIAID)Influenza, Influenza Immunisation

Start: 2018-09-25End: 2020-12-22Updated: 2022-03-18

Related Papers

A phase I study of the safety, reactogenicity and immunogenicity of two quadrivalent seasonal influenza vaccines (Fluzone® or Flublok®) with or without one of two adjuvants (AF03 or Advax-CpG55.2) in healthy adults 18-45 years of age.

2025-03-182 citations

Anti-neuraminidase and anti-hemagglutinin stalk responses to different influenza a(H7N9) vaccine regimens.

2025-01-042 citations

Phase 1 dose-escalation trial evaluating a group 2 influenza hemagglutinin stabilized stem nanoparticle vaccine

npj Vaccines2024-09-1715 citations

Safety and immunogenicity of monovalent H7N9 influenza vaccine with AS03 adjuvant given sequentially or simultaneously with a seasonal influenza vaccine: A randomized clinical trial.

2022-04-227 citations

A Phase 1 Randomized Placebo-Controlled Study to Assess the Safety, Immunogenicity and Genetic Stability of a New Potential Pandemic H7N9 Live Attenuated Influenza Vaccine in Healthy Adults

Vaccines2020-06-107 citations