Individual Patient TCR-Transduced PBL
Sponsors
National Cancer Institute (NCI), National Institutes of Health Clinical Center (CC)
Conditions
Blood CancerBreast CancerDysmyelopoietic SyndromesEndocrine TumorsGastrointestinal/Genitourinary CancersHematological NeoplasmsHematopoetic MyelodysplasiaHematopoietic Malignancies
Phase 1
Phase 2
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer
RecruitingNCT03412877
Start: 2018-09-06End: 2029-03-23Target: 285Updated: 2026-08-24
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated or Viral Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab
WithdrawnNCT04536922
Start: 2021-01-27End: 2021-01-27Updated: 2021-02-01