Inactivated Influenza Vaccine

BIOLOGICAL15 trials

Sponsors

The University of Hong Kong, St. Jude Children's Research Hospital, University of Rochester, Hualan Biological Engineering, Inc., Protein Sciences Corporation

Conditions

CancerChronic Lymphocytic LeukemiaDiffuse Large B-Cell LymphomaFollicular LymphomaHealthy Young AdultsHuman InfluenzaInfluenzaInfluenza Vaccine Response

Phase 1

A Study of a Live Intranasal Influenza Vaccine in Children With Cancer

CompletedNCT00906750

St. Jude Children's Research HospitalCancer

Start: 2008-10-31End: 2011-07-31Updated: 2011-10-13

Inactivated Influenza Vaccine Delivered by Microneedle Patch or by Hypodermic Needle

CompletedNCT02438423

Mark PrausnitzInfluenza

Start: 2015-06-30End: 2016-03-23Updated: 2019-07-05

The Safety, Tolerance, and Immunogenicity of MAS-1-Adjuvanted Seasonal Inactivated Influenza Vaccine (MER4101)

Nova Immunotherapeutics LimitedInfluenza, Human

Start: 2015-07-31End: 2020-12-31Updated: 2019-09-06

Phase 2

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in Healthy Adults

CompletedNCT05606965

ModernaTX, Inc.Influenza

Start: 2022-11-02End: 2025-11-13Updated: 2025-11-24

Phase 3

Clinical Trial of the Inactivated Influenza Vaccine (0.25ml Formulation for Pediatric Use)

CompletedNCT01554826

Hualan Biological Engineering, Inc.Influenza

Start: 2009-03-31End: 2010-02-28Updated: 2012-09-06

Protective Efficacy of Flublok® Quadrivalent Versus Licensed Inactivated Influenza Vaccine in Adults ≥50 Years of Age

CompletedNCT02285998

Protein Sciences CorporationInfluenza

Start: 2014-10-31End: 2015-05-31Updated: 2017-10-27

Phase 4

Study of Live, Attenuated Influenza Vaccination in Preterm and Full-Term Infants

TerminatedNCT01194297

University of RochesterInfluenza

Start: 2010-08-31End: 2012-05-31Updated: 2014-08-22

Live Attenuated Influenza Vaccine (LAIV) Versus Trivalent Inactivated Influenza Vaccine in Healthy Adults 18-49 Years

CompletedNCT03101462

St. Louis UniversityInfluenza

Start: 2011-02-24End: 2011-11-09Updated: 2019-03-06

Flu Vaccine Responses in the Setting of Melanoma Treatment

Active, not recruitingNCT03315975

University of PennsylvaniaViral Vaccines

Start: 2017-10-20End: 2026-07-01Target: 40Updated: 2025-08-19

An Effectiveness Trial to Evaluate Protection of Children and Pregnant Women by Influenza Vaccine in Rural Bangladesh

Active, not recruitingNCT04998344

University of BergenInfluenza Viral Infections

Start: 2021-04-07End: 2024-12-31Target: 3800Updated: 2024-04-19

Characterizing the Human Airway Immune Response to FluMist Vaccination

RecruitingNCT07177417

Washington University School of MedicineHealthy Young Adults, Influenza Vaccine Response, Influenza Vaccines

Start: 2025-09-09End: 2028-11-30Target: 30Updated: 2025-09-17

Unknown Phase

Direct and Indirect Benefits of Influenza Vaccine Versus Placebo in Healthy Children

CompletedNCT00792051

The University of Hong KongInfluenza Virus Infection

Start: 2008-09-30End: 2010-12-31Target: 2800Updated: 2014-12-30

Post-marketing Clinical Observation of an Inactivated Influenza Split Vaccine

CompletedNCT01568788

Hualan Biological Engineering, Inc.Human Influenza

Start: 2008-12-31End: 2009-03-31Updated: 2012-06-20

Post-Marketing Observational Study of Safety Following Vaccination With Flublok® Compared to Licensed IIV in Adults

CompletedNCT02600585

Protein Sciences CorporationHuman Influenza

Start: 2015-11-30End: 2016-09-30Updated: 2017-10-12

Evaluation of Human Immune Responses Vaccination in Patients With Lymphoma

RecruitingNCT03501576

Emory UniversityChronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma +2

Start: 2018-04-06End: 2026-05-26Target: 200Updated: 2026-02-11

Related Papers

Influenza antibody breadth and effector functions are immune correlates from acquisition of pandemic infection of children.

2024-04-134 citations

Safety and immunogenicity of a phase 1/2 randomized clinical trial of a quadrivalent, mRNA-based seasonal influenza vaccine (mRNA-1010) in healthy adults: interim analysis.

2023-06-1984 citations

A phase 1 dose-sparing, randomized clinical trial of seasonal trivalent inactivated influenza vaccine combined with MAS-1, a novel water-in-oil adjuvant/delivery system.

2022-02-048 citations

MAS-1, a novel water-in-oil adjuvant/delivery system, with reduced seasonal influenza vaccine hemagglutinin dose may enhance potency, durability and cross-reactivity of antibody responses in the elderly.

2022-02-041 citations

The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial.

2017-06-27296 citations

Efficacy of Recombinant Influenza Vaccine in Adults 50 Years of Age or Older

New England Journal of Medicine2017-06-21274 citations

Incidence of Influenza Virus Infections in Children in Hong Kong in a 3-Year Randomized Placebo-Controlled Vaccine Study, 2009-2012

Clinical Infectious Diseases2014-05-1364 citations

Protective efficacy against pandemic influenza of seasonal influenza vaccination in children in Hong Kong: a randomized controlled trial.

2012-06-0558 citations

Safety and immunogenicity of live attenuated and inactivated influenza vaccines in children with cancer.

2011-09-2334 citations

Protective efficacy of seasonal influenza vaccination against seasonal and pandemic influenza virus infection during 2009 in Hong Kong.

2010-11-10124 citations