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Inactivated COVID-19 vaccine

BIOLOGICAL12 trials

Sponsors

Sinovac Research and Development Co., Ltd., China National Biotec Group Company Limited, Sinovac Life Sciences Co., Ltd., Yisheng Biopharma (Singapore) Pte. Ltd.

Conditions

COPDCOVID-19Chronic BronchitisCopdCovid-19 VaccineHIV Infections

Phase 2

A Phase II/III Study of PIKA Recombinant SARS-CoV-2 Vaccine as a Booster Dose.
CompletedNCT05463419
Yisheng Biopharma (Singapore) Pte. Ltd.Covid-19 Vaccine
Start: 2022-10-03End: 2024-04-11Updated: 2024-07-23

Phase 3

Efficacy, Immunogenicity and Safety of COVID-19 Vaccine , Inactivated in Children and Adolescents
CompletedNCT04992260
Sinovac Research and Development Co., Ltd.COVID-19
Start: 2021-09-10End: 2023-05-31Updated: 2023-10-16

Phase 4

Immunogenicity and Safety of an Inactivated COVID-19 Vaccine
CompletedNCT04953325
Sinovac Research and Development Co., Ltd.COVID-19
Start: 2021-07-09End: 2022-01-31Updated: 2022-04-14
Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in Elderly People With Chronic Bronchitis and COPD
NCT05075083
China National Biotec Group Company LimitedChronic Bronchitis, COPD, COVID-19
Start: 2021-10-08End: 2022-06-30Target: 400Updated: 2021-10-22
Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in Patients Aged ≥60 Years With Chronic Bronchitis and COPD
NCT05075057
China National Biotec Group Company LimitedChronic Bronchitis, Copd, COVID-19
Start: 2021-10-08End: 2022-06-30Target: 400Updated: 2021-10-22
Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in People With HIV Infected
NCT05075070
China National Biotec Group Company LimitedCOVID-19, HIV Infections
Start: 2021-10-08End: 2022-06-30Target: 400Updated: 2021-10-22
Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in People Aged ≥18 Years With HIV Infected
NCT05075044
China National Biotec Group Company LimitedCOVID-19, HIV Infections
Start: 2021-10-08End: 2022-12-30Target: 400Updated: 2021-10-22
Immunogenicity and Safety of a Third Dose and Immune Persistence of BBIBP-Corv Vaccine in Elderly People With Chronic Bronchitis and COPD
NCT05104216
China National Biotec Group Company LimitedChronic Bronchitis, COPD, COVID-19
Start: 2021-12-31End: 2022-06-30Target: 400Updated: 2021-11-02
Immunogenicity and Safety of a Third Dose and Immune Persistence of BBIBP-Corv Vaccine in People With HIV Infected
NCT05105295
China National Biotec Group Company LimitedCOVID-19, HIV Infections
Start: 2021-12-31End: 2022-06-30Target: 400Updated: 2021-11-03
Immunogenicity of an Inactivated COVID-19 Vaccine
CompletedNCT05198336
Sinovac Research and Development Co., Ltd.COVID-19
Start: 2022-01-08End: 2022-12-30Updated: 2023-09-25
Immunogenicity，Safety and Cross - Immune Response With Mutant Strains of a Third Dose of an Inactivated COVID-19 Vaccine
NCT05329038
Sinovac Life Sciences Co., Ltd.COVID-19
Start: 2022-04-19End: 2024-02-20Target: 180Updated: 2023-11-07

Unknown Phase

Effectiveness of COVID-19 Vaccine for Prevention of COVID-19 in the Dominican Republic
CompletedNCT04974164
Sinovac Research and Development Co., Ltd.COVID-19
Start: 2021-08-17End: 2021-12-13Updated: 2022-08-23

Related Papers

Inadequate immune response to inactivated COVID-19 vaccine among older people living with HIV: a prospective cohort study
Journal of Virology2025-08-213 citations
Safety and immunogenicity of PIKA-adjuvanted recombinant SARS-CoV-2 spike protein subunit vaccine as a booster against SARS-CoV-2: a phase II, open-label, randomized, double-blinded study.
2024-10-31
Efficacy, immunogenicity and safety of CoronaVac® in children and adolescents aged 6 months to 17 years: a multicenter, randomized, double-blind, placebo-controlled phase III clinical trial
Nature Communications2024-08-061 citations
Immune responses during COVID-19 breakthrough cases in vaccinated children and adolescents
Frontiers in Immunology2024-05-152 citations
Extending the dosing interval of COVID-19 vaccination leads to higher rates of seroconversion in people living with HIV
Frontiers in Immunology2023-03-0210 citations
Inactivated Vaccine-Induced SARS-CoV-2 Variant-Specific Immunity in Children.
2022-11-1622 citations
Differences in the immune response elicited by two immunization schedules with an inactivated SARS-CoV-2 vaccine in a randomized phase 3 clinical trial
eLife2022-10-1313 citations
SARS-CoV-2 vaccine booster in solid organ transplant recipients previously immunised with inactivated versus mRNA vaccines: A prospective cohort study.
2022-09-2318 citations