inactivé)
Sponsors
GlaxoSmithKline Biologicals, GlaxoSmithKline Biologicals, Janssen Vaccines & Prevention B.V., CHU De Liege, Osivax
Conditions
Healthy volunteers (prevention of influenza infection)Hematological cancerInfluenza diseasePrevention of invasive extraintestinal pathogenic Escherichia coli (ExPEC) disease
Phase 1
A Phase 1/2, randomized, dose-finding/dose-confirmation study to evaluate the reactogenicity, safety and immunogenicity of mRNA-based multivalent seasonal influenza vaccine candidates administered in healthy younger and older adults
CompletedCTIS2022-502308-66-00
Start: 2023-04-27End: 2024-07-02Target: 438Updated: 2024-05-27
Phase 1/2, first-in-human, randomized, double-blind, reference-controlled study to evaluate the safety and immunogenicity of an extemporaneously mixed Combo Inactivated Influenza Vaccine (Green Cross [GC]-IIV; 15µg of each hemagglutinin [HA])/OVX836 (480µg), in comparison to GC-IIV (15µg of each HA) concomitantly administered with OVX836 (480µg), GC-IIV alone (15 µg each HA), OVX836 alone (480µg), and a licensed reference trivalent IIV (Vaxigrip®; 15µg of each HA), administered intramuscularly (IM) in healthy participants
Not yet recruitingCTIS2026-526939-19-00
Target: 250Updated: 2026-09-04
Phase 3
A Single-Blind randomized trial of High-Dose versus Standard-Dose Inactivated Influenza Vaccine in Adult Patients Treated for an Hematological Cancer (Flu-Hemato-Rando study)
RecruitingCTIS2023-505357-40-00
Start: 2023-09-18Target: 180Updated: 2023-08-23
A Phase 3 Randomized Double-blind Controlled Study to Evaluate the Immunogenicity, Safety, and Reactogenicity of ExPEC9V and High-dose Quadrivalent Influenza Vaccine, With and Without Co-administration, in Adults Aged 65 Years or Older
CompletedCTIS2023-504168-40-00
Start: 2023-11-06End: 2024-07-26Target: 400Updated: 2024-06-11