In the POBASCAM trial, the addition of a high-risk human papillomavirus (hrHPV) test to the regular cervical screening programme to improve detection of precursor lesions of cervical cancer is evaluat

2 trials

Sponsors

Vrije University Medical Centre (VUMC) (The Netherlands), - Department of Pathology, VU University Medical Center - Department of Pathology, Spaarne Ziekenhuis, Hoofddorp - Leiden Cytology and Pathology Laboratory, Leiden - Stichting PA Laboratorium Kennemerland, Haarlem

Conditions

Cervical intraepithelial neoplasia Cancer Cervical cancerCervical intraepithelial neoplasia and cervical cancer. Due to the low prevalence of invasive cervical cancer in the Netherlands, and the aim of cervical screening to prevent the occurrence of and death caused by to cervical cancer, we evaluate the prevalence of a surrogate marker for cervical cancer incidence, namely the immediate precursor lesion of cervical cancer cervical intra-epithelial neoplasia grade 3.

Unknown Phase

HrHPV in the population research on cervical cancer.

Active, not recruitingNL-OMON28695

- Department of Pathology, VU University Medical Center - Department of Pathology, Spaarne Ziekenhuis, Hoofddorp - Leiden Cytology and Pathology Laboratory, Leiden - Stichting PA Laboratorium Kennemerland, HaarlemCervical intraepithelial neoplasia and cervical cancer. Due to the low prevalence of invasive cervical cancer in the Netherlands, and the aim of cervical screening to prevent the occurrence of and death caused by to cervical cancer, we evaluate the prevalence of a surrogate marker for cervical cancer incidence, namely the immediate precursor lesion of cervical cancer cervical intra-epithelial neoplasia grade 3.

Start: 1999-01-01Target: 44102Updated: 2024-02-28

High-risk human papillomavirus (HrHPV) in the population research on cervical cancer

Active, not recruitingISRCTN20781131

Vrije University Medical Centre (VUMC) (The Netherlands)Cervical intraepithelial neoplasia Cancer Cervical cancer

Start: 1999-01-01Target: 44102Updated: 2022-11-14

Related Papers

Risk of cervical precancer among HPV–negative women in the Netherlands and its association with previous HPV and cytology results: A follow-up analysis of a randomized screening study

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Cervical cancer risk in HPV‐positive women after a negative <i>FAM19A4/mir124‐2</i> methylation test: A post hoc analysis in the POBASCAM trial with 14 year follow‐up

International Journal of Cancer2018-04-17111 citations

Safety of extending screening intervals beyond five years in cervical screening programmes with testing for high risk human papillomavirus: 14 year follow-up of population based randomised cohort in the Netherlands

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Human papillomavirus testing for the detection of high-grade cervical intraepithelial neoplasia and cancer: final results of the POBASCAM randomised controlled trial.

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Human papillomavirus DNA testing for the detection of cervical intraepithelial neoplasia grade 3 and cancer: 5-year follow-up of a randomised controlled implementation trial.

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