IMVT-1402
Sponsors
Immunovant Sciences GmbH
Conditions
ACPA-Positive Rheumatoid ArthritisChronic Cutaneous Lupus ErythematosusChronic Inflammatory Demyelinating Polyneuropathy (CIDP)Cutaneous lupus erythematosusGeneralized Myasthenia GravisGraves' DiseaseGraves’ DiseaseGrave’s Disease
Phase 2
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
RecruitingNCT06727604
Start: 2024-12-17End: 2028-06-01Target: 240Updated: 2026-08-25
A Study to Evaluate the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult to Treat Rheumatoid Arthritis
Active, not recruitingNCT06754462
Start: 2025-01-10End: 2027-09-01Target: 120Updated: 2026-04-22
A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE)
Active, not recruitingNCT06980805
Start: 2025-02-19End: 2027-04-01Target: 56Updated: 2026-08-28
Efficacy and Safety of IMVT-1402 in Adult Participants With Primary Sjogren's Disease With Moderate to Severe Systemic Disease Activity
Active, not recruitingNCT06979531
Start: 2025-06-30End: 2029-07-01Target: 180Updated: 2026-09-10
A Phase 2b, Multicenter, Double-blind, Placebo-controlled Randomized Withdrawal Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult-to-Treat, ACPA-Positive Rheumatoid Arthritis
Active, not recruitingCTIS2024-515973-82-00
Start: 2025-06-23Target: 168Updated: 2026-01-27
A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Patients With Graves' Disease
RecruitingCTIS2024-516020-33-00
Start: 2025-06-26Target: 158Updated: 2025-12-08
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
RecruitingNCT07018323
Start: 2025-06-19End: 2027-05-01Target: 210Updated: 2026-08-25
A Phase 2b, Randomized, Double-blind, Placebo-controlled Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants with Active Subacute Cutaneous Lupus Erythematosus (SCLE) and/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations.
RecruitingCTIS2024-516745-39-00
Start: 2025-07-11Target: 46Updated: 2026-01-26
A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Patients With Graves' Disease
RecruitingCTIS2025-521920-31-00
Start: 2025-11-21Target: 110Updated: 2025-11-05
A Phase 2b, Multi-center, Randomized, Double-blind, Placebo controlled Study of IMVT-1402 Treatment in Adult Participants with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
RecruitingCTIS2024-517614-14-00
Start: 2025-11-28Target: 79Updated: 2026-01-16
A Phase 2b, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants with Primary Sjogren’s Disease with Moderate to Severe Systemic Disease Activity
RecruitingCTIS2025-520831-18-00
Start: 2025-12-12Target: 72Updated: 2025-12-02
A Long-Term Extension Study of IMVT-1402 in Adult Participants With Graves' Disease (GD)
Enrolling by invitationNCT07286006
Start: 2026-01-26End: 2030-03-01Target: 372Updated: 2026-07-27
A Long-Term Extension Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Patients With Graves' Disease
Not yet recruitingCTIS2025-524001-33-00
Target: 33Updated: 2026-05-06
Phase 3
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis
RecruitingNCT07039916
Start: 2025-05-27End: 2028-12-01Target: 231Updated: 2026-07-30
A Phase 3, Multicenter, Randomized, Placebo-Controlled, Double-Blind Study to Assess the Efficacy and Safety of IMVT-1402 in Patients With Mild to Severe Generalized Myasthenia Gravis
RecruitingCTIS2024-515979-35-00
Start: 2025-11-13Target: 78Updated: 2025-10-27