Immunosuppressive Therapy (IST)

PROCEDURE3 trials

Sponsors

Michael Pulsipher, Boston Children's Hospital, Anjali Sharathkumar

Conditions

Aplastic AnemiaSevere Aplastic Anemia

Phase 2

UI-Romi-02; Romiplostim Added to Standard of Care for Treatment Naive and Relapsed or Refractory Severe Aplastic Anemia

Not yet recruitingNCT07001254

Anjali SharathkumarAplastic Anemia

Start: 2026-08-01End: 2031-12-31Target: 15Updated: 2025-12-19

Phase 3

A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)

Active, not recruitingNCT05600426

Boston Children's HospitalSevere Aplastic Anemia

Start: 2023-01-25End: 2029-12-01Updated: 2026-07-30

Unknown Phase

Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia

CompletedNCT02845596

Michael PulsipherSevere Aplastic Anemia

Start: 2016-08-31End: 2023-07-19Target: 40Updated: 2025-05-11