Image-guided Radiotherapy

RADIATION4 trials

Sponsors

St. Jude Children's Research Hospital, CancerCare Manitoba, University Health Network, Toronto

Conditions

Musculoskeletal TumorsProstate CancerProstate Cancer (Adenocarcinoma)Prostatic NeoplasmsRhabdomyosarcomaSarcoma, Ewing'sSoft Tissue Sarcoma

Phase 2

Radiation Therapy to Treat Musculoskeletal Tumors

Active, not recruitingNCT00186992

St. Jude Children's Research HospitalMusculoskeletal Tumors, Rhabdomyosarcoma, Sarcoma, Ewing's +1

Start: 2003-01-10End: 2029-10-01Updated: 2026-03-04

Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvolved Areas in Salvage Radiotherapy Using SBRT for Prostate Cancer to Reduce Treatment Toxicity

Not yet recruitingNCT07515651

University Health Network, TorontoProstate Cancer (Adenocarcinoma)

Start: 2026-05-01End: 2034-05-01Target: 50Updated: 2026-04-07

Unknown Phase

Prostate Accurately Targeted Radiotherapy Investigation of Overall Treatment Time

CompletedNCT01423474

CancerCare ManitobaProstatic Neoplasms

Start: 2012-01-31End: 2019-08-31Updated: 2024-02-23

Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvolved Areas in Salvage Radiotherapy for Prostate Cancer

RecruitingNCT05328505

University Health Network, TorontoProstate Cancer

Start: 2022-08-23End: 2030-08-01Target: 80Updated: 2026-03-24

Related Papers

Every Other Day or Once a Week: Long-term Oncological Outcomes in the Phase 2 PATRIOT Trial of Prostate Stereotactic Ablative Body Radiotherapy

European Urology Oncology2025-04-26

Every-other-day or once-a-week: Long-term efficacy outcomes of the multicenter randomised PATRIOT prostate SBRT trial.

Journal of Clinical Oncology2024-01-291 citations

Study protocol of a randomised controlled trial of prostate radiotherapy in high-risk and node-positive disease comparing moderate and extreme hypofractionation (PRIME TRIAL)

BMJ Open2020-02-0127 citations

Long-term results of a phase II study of hypofractionated proton therapy for prostate cancer: moderate versus extreme hypofractionation

Radiation Oncology2019-01-1024 citations

Once-weekly versus every-other-day stereotactic body radiotherapy in patients with prostate cancer (PATRIOT): A phase 2 randomized trial.

2018-03-1553 citations

PATRIOT Trial: Randomized phase II study of prostate stereotactic body radiotherapy comparing 11 versus 29 days overall treatment time.

Journal of Clinical Oncology2015-03-0113 citations