Image-Guided Adaptive Radiation Therapy

RADIATION8 trials

Conditions

Adenocarcinoma of the LungAdult Hepatocellular CarcinomaHead and Neck CancerLarge Cell Lung CancerLocalized Prostate AdenocarcinomaMalignant Prostate NeoplasmMelanomaMetastatic Malignant Neoplasm in the Liver

Early Phase 1

MRI-Guided Stereotactic Body Radiation Therapy in Treating Patients With Liver Metastases or Liver Cancer

CompletedNCT02683200

Jonsson Comprehensive Cancer CenterAdult Hepatocellular Carcinoma, Metastatic Malignant Neoplasm in the Liver

Start: 2015-06-03End: 2022-01-01Updated: 2023-02-21

Phase 1

Phase I Study of IMRT and Molecular-Image Guided Adaptive Radiation Therapy for Advanced HNSCC

TerminatedNCT01283178

Virginia Commonwealth UniversitySalivary Gland Squamous Cell Carcinoma, Stage III Salivary Gland Cancer, Stage III Squamous Cell Carcinoma of the Hypopharynx +13

Start: 2011-07-31End: 2016-09-30Updated: 2016-10-31

Phase I IGART Study Using Active Breathing Control and Simultaneous Boost for Patients With NSCLC

WithdrawnNCT02059967

Virginia Commonwealth UniversityAdenocarcinoma of the Lung, Large Cell Lung Cancer, Squamous Cell Lung Cancer +4

Start: 2014-03-31End: 2015-01-31Updated: 2015-03-19

Phase 2

Study of Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy in Patients With Stage III Non-small Cell Lung Cancer

NCT01507428

National Cancer Institute (NCI)Stage IIIA Lung Non-Small Cell Cancer AJCC v7, Stage IIIB Lung Non-Small Cell Cancer AJCC v7, Stage III Lung Non-Small Cell Cancer AJCC v7

Start: 2012-02-22End: 2021-08-01Updated: 2021-04-29

Unknown Phase

Image-Guided Adaptive Radiotherapy for in Detecting Tumors During Treatment in Patients With Head and Neck Cancer

CompletedNCT01843673

Virginia Commonwealth UniversityHead and Neck Cancer

Start: 2009-01-31End: 2015-01-31Updated: 2016-07-06

Adaptive Staged Stereotactic Body Radiation Therapy in Treating Patients With Spinal Metastases That Cannot Be Removed by Surgery

CompletedNCT02527304

Albert Einstein College of MedicineMelanoma, Metastatic Malignant Neoplasm in the Spine, Renal Cell Carcinoma +2

Start: 2015-06-30End: 2018-05-31Updated: 2024-03-06

Daily Adaptive Post-Prostatectomy With Stereotactic Ablative Radiotherapy in Patients With Prostate Cancer

Active, not recruitingNCT05830838

Mayo ClinicMalignant Prostate Neoplasm

Start: 2023-07-28End: 2029-05-30Updated: 2025-05-21

Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer

RecruitingNCT06325046

Mayo ClinicLocalized Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8 +1

Start: 2024-08-15End: 2031-08-30Target: 144Updated: 2026-03-31

Journal of Clinical Oncology2024-10-0429 citations

NRG-RTOG 1106/ACRIN 6697: A phase IIR trial of standard versus adaptive (mid-treatment PET-based) chemoradiotherapy for stage III NSCLC—Results and comparison to NRG-RTOG 0617 (non-personalized RT dose escalation).

Journal of Clinical Oncology2021-05-2031 citations

Delineation of lung cancer with FDG PET/CT during radiation therapy.

2018-11-1216 citations

FDG and FMISO PET-guided dose escalation with intensity-modulated radiotherapy in lung cancer.

2018-10-2332 citations

Abstract IA16: Midtreatment metabolic imaging as a biomarker of treatment response

Clinical Cancer Research2017-11-30