Image Guided Radiation Therapy
Sponsors
M.D. Anderson Cancer Center, Thomas Zilli, National Cancer Institute (NCI), NRG Oncology, OHSU Knight Cancer Institute
Conditions
Basaloid Squamous Cell CarcinomaBreast CancerClinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Eyelid Squamous Cell CarcinomaHead and Neck Squamous Cell CarcinomaHypopharyngeal Squamous Cell Carcinoma
Phase 1
Image-Guided, Intensity-Modulated Photon or Proton Beam Radiation Therapy in Treating Patients With Stage II-IIIB Non-small Cell Lung Cancer
Active, not recruitingNCT01629498
Start: 2012-09-17End: 2027-09-30Updated: 2026-03-09
Trametinib, Combination Chemotherapy, and Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
TerminatedNCT01912625
Start: 2013-10-28End: 2023-02-24Updated: 2023-05-06
Biology-Guided Radiation Therapy for the Treatment of Patients With Bone Metastases
SuspendedNCT06549478
Start: 2024-07-26End: 2027-01-26Target: 24Updated: 2026-09-10
Phase 2
Nab-paclitaxel and Gemcitabine Hydrochloride Followed by Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery
CompletedNCT02427841
Start: 2016-01-21End: 2022-12-12Updated: 2023-09-06
Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery
Active, not recruitingNCT03493425
Start: 2019-03-12End: 2029-03-31Target: 82Updated: 2026-08-19
De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer
Active, not recruitingNCT03952585
Start: 2019-10-09End: 2026-12-11Updated: 2026-07-02
Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer
WithdrawnNCT06084845
Start: 2024-04-12End: 2028-05-31Updated: 2024-07-25
Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial
RecruitingNCT06499870
Start: 2024-09-06End: 2032-11-19Target: 50Updated: 2026-06-05
Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer
RecruitingNCT06532279
Start: 2025-06-23End: 2032-01-01Target: 98Updated: 2026-08-17
Phase 3
Radiation Therapy vs. Observation Following Gemcitabine and Cisplatin for Inoperable Localized Liver Cancer
TerminatedNCT02200042
Start: 2014-09-29End: 2018-07-02Updated: 2026-07-13
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
RecruitingNCT05624996
Start: 2023-07-12End: 2036-10-15Target: 474Updated: 2026-08-17
Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer
SuspendedNCT06568172
Start: 2025-02-18End: 2031-08-14Target: 420Updated: 2026-09-01
Unknown Phase
Hypofractionated Radiation Therapy in Prostate Cancer
NCT01764646
Start: 2012-09-30End: 2025-09-30Updated: 2020-05-19
Development of Real-time Image-guided Radiotherapy
TerminatedNCT03524248
Start: 2012-05-17End: 2018-07-19Updated: 2020-03-02
Phase II Study of Daily Adaptive Radiotherapy for Submandibular Gland-sparing in Head and Neck Cancer
RecruitingNCT07348887
Start: 2025-10-15End: 2029-10-01Target: 50Updated: 2026-03-04