Image Guided Radiation Therapy
Sponsors
M.D. Anderson Cancer Center, Thomas Zilli, National Cancer Institute (NCI), NRG Oncology, OHSU Knight Cancer Institute
Conditions
Basaloid Squamous Cell CarcinomaBreast CancerClinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Eyelid Squamous Cell CarcinomaHead and Neck Squamous Cell CarcinomaHypopharyngeal Squamous Cell Carcinoma
Phase 1
Image-Guided, Intensity-Modulated Photon or Proton Beam Radiation Therapy in Treating Patients With Stage II-IIIB Non-small Cell Lung Cancer
Active, not recruitingNCT01629498
Start: 2012-09-17End: 2027-09-30Updated: 2026-03-09
Trametinib, Combination Chemotherapy, and Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
TerminatedNCT01912625
Start: 2013-10-28End: 2023-02-24Updated: 2023-05-06
Biology-Guided Radiation Therapy for the Treatment of Patients With Bone Metastases
RecruitingNCT06549478
Start: 2024-07-26End: 2027-01-26Target: 24Updated: 2025-09-17
Phase 2
Nab-paclitaxel and Gemcitabine Hydrochloride Followed by Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery
CompletedNCT02427841
Start: 2016-01-21End: 2022-12-12Updated: 2023-09-06
Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery
RecruitingNCT03493425
Start: 2019-03-12End: 2029-03-31Target: 82Updated: 2026-03-23
De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer
Active, not recruitingNCT03952585
Start: 2019-10-09End: 2026-12-11Updated: 2026-04-03
Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer
WithdrawnNCT06084845
Start: 2024-04-12End: 2028-05-31Updated: 2024-07-25
Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial
RecruitingNCT06499870
Start: 2024-09-06End: 2032-11-19Target: 50Updated: 2025-10-21
Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer
RecruitingNCT06532279
Start: 2024-12-16End: 2027-01-01Target: 98Updated: 2026-04-03
Phase 3
Radiation Therapy vs. Observation Following Gemcitabine and Cisplatin for Inoperable Localized Liver Cancer
TerminatedNCT02200042
Start: 2014-09-29End: 2018-07-02Updated: 2019-08-28
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
RecruitingNCT05624996
Start: 2023-07-12End: 2031-10-15Target: 474Updated: 2026-04-03
Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer
RecruitingNCT06568172
Start: 2025-02-18End: 2031-08-14Target: 420Updated: 2026-04-03
Unknown Phase
Hypofractionated Radiation Therapy in Prostate Cancer
NCT01764646
Start: 2012-09-30End: 2025-09-30Updated: 2020-05-19
Development of Real-time Image-guided Radiotherapy
TerminatedNCT03524248
Start: 2012-05-17End: 2018-07-19Updated: 2020-03-02
Phase II Study of Daily Adaptive Radiotherapy for Submandibular Gland-sparing in Head and Neck Cancer
RecruitingNCT07348887
Start: 2025-10-15End: 2029-10-01Target: 50Updated: 2026-03-04