iFR

DEVICE4 trials

Sponsors

Imperial College London, Uppsala University, Radboud University Medical Center, Volcano Corporation

Conditions

Acute Myocardial InfarctionAngina PectorisCardiac IschemiaCoronary Artery DiseaseCoronary StenosisMulti Vessel Coronary Artery Disease

Unknown Phase

Functional Lesion Assessment of Intermediate Stenosis to Guide Revascularisation

Imperial College LondonCoronary Artery Disease

Start: 2014-01-31End: 2021-01-19Target: 2500Updated: 2019-08-14

Evaluation of iFR vs FFR in Stable Angina or Acute Coronary Syndrome

CompletedNCT02166736

Uppsala UniversityAcute Myocardial Infarction, Angina Pectoris

Start: 2014-05-31End: 2016-12-31Updated: 2017-01-12

iFR Guided Multi-vessel Revascularization During Percutaneous Coronary Intervention for Acute Myocardial Infarction

Active, not recruitingNCT03298659

Radboud University Medical CenterAcute Myocardial Infarction, Multi Vessel Coronary Artery Disease

Start: 2017-12-21End: 2027-05-31Updated: 2025-04-04

Radiographic Imaging Validation and EvALuation for Angio iFR (ReVEAL iFR)

CompletedNCT03857503

Volcano CorporationCardiac Ischemia, Coronary Artery Disease, Coronary Stenosis

Start: 2019-08-01End: 2021-03-12Updated: 2021-04-01

Related Papers

Immediate or Deferred Nonculprit-Lesion PCI in Myocardial Infarction.

2025-10-28

Accuracy of instantaneous wave-free ratio and fractional flow reserve derived from single coronary angiographic projections.

2025-03-11

Physiological Disease Pattern as Assessed by Pull Back Pressure Gradient Index in Vessels With FFR/iFR Discordance.

2025-02-1910 citations

Coronary Revascularization Guided With Fractional Flow Reserve or Instantaneous Wave-Free Ratio

JAMA Cardiology2024-10-1616 citations

Instantaneous wave free ratio vs. fractional flow reserve and 5-year mortality: iFR SWEDEHEART and DEFINE FLAIR.

2023-11-0131 citations

Clinical Outcome of Revascularization Deferral With Instantaneous Wave‐Free Ratio and Fractional Flow Reserve: A 5‐Year Follow‐Up Substudy From the iFR‐SWEDEHEART Trial

Journal of the American Heart Association2023-02-0325 citations

5-Year Outcomes of PCI Guided by Measurement of Instantaneous Wave-Free Ratio Versus Fractional Flow Reserve.

2022-03-0144 citations

Instantaneous wave-free ratio guided multivessel revascularisation during percutaneous coronary intervention for acute myocardial infarction: study protocol of the randomised controlled iMODERN trial

BMJ Open2021-01-017 citations

Sex Differences in Instantaneous Wave-Free Ratio or Fractional Flow Reserve-Guided Revascularization Strategy.

2019-10-0123 citations

Comparison of Major Adverse Cardiac Events Between Instantaneous Wave-Free Ratio and Fractional Flow Reserve–Guided Strategy in Patients With or Without Type 2 Diabetes

JAMA Cardiology2019-07-1736 citations

Instantaneous Wave-free Ratio versus Fractional Flow Reserve to Guide PCI

New England Journal of Medicine2017-03-18937 citations

Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI

New England Journal of Medicine2017-03-18926 citations