Icalcaprant
Sponsors
AbbVie
Conditions
Bipolar I DisorderBipolar II DisorderHealthy VolunteerMajor Depressive Disorder
Phase 1
A Study to Assess Change in How Oral Icalcaprant With Itraconazole Moves Through the Body in Healthy Adult Participants
CompletedNCT06722430
Start: 2024-11-13End: 2025-01-13Updated: 2025-01-28
A Single Dose Study to Assess Adverse Events and How Oral Icalcaprant Moves Through the Body in Healthy Adult Japanese and Han Chinese Participants
CompletedNCT06722417
Start: 2024-11-26End: 2025-01-17Updated: 2025-01-28
Phase 2
A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
RecruitingNCT06696755
Start: 2026-02-03End: 2027-11-01Target: 195Updated: 2026-04-03
A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder
RecruitingNCT07276997
Start: 2025-12-18End: 2027-09-01Target: 195Updated: 2026-03-23