hypofractionated radiotherapy with immunotherapy

RADIATION3 trials

Sponsors

Anhui Provincial Hospital, Peking University Cancer Hospital & Institute, Children's National Research Institute

Conditions

ATRT RecurrentCNS MalignanciesEmbryonal NeoplasmEpendymoma RecurrentHigh Grade GliomasMedulloblastoma RecurrentNon-Small Cell Lung CancerPineoblastoma

Early Phase 1

A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies.

RecruitingNCT07017816

Children's National Research InstituteATRT Recurrent, CNS Malignancies, Embryonal Neoplasm +4

Start: 2025-12-16End: 2028-05-01Target: 18Updated: 2026-04-29

Phase 1

Hypofractionated Radiotherapy Combined with Immunotherapy for Limited-stage Small-cell Lung Cancer

RecruitingNCT06527898

Anhui Provincial HospitalSmall-cell Lung Cancer

Start: 2024-07-01End: 2027-07-31Target: 45Updated: 2024-09-19

Phase 2

Immunotherapy Combined with Hypofractionated Concurrent Chemoradiotherapy Followed by Immunotherapy in LA-NSCLC

RecruitingNCT06849167

Peking University Cancer Hospital & InstituteNon-Small Cell Lung Cancer

Start: 2025-03-01End: 2030-03-01Target: 63Updated: 2025-02-27