Hypertonic 3% saline

DRUG4 trials

Sponsors

Institute of Liver and Biliary Sciences, India, University Hospital, Basel, Switzerland, Rochester General Hospital, Cairo University

Conditions

Acute Liver FailureCerebral EdemaHealthy AgeingHyponatremia SymptomaticOsmotic Demyelination SyndromeSymptomatic Irreversible Pulpitis (SIP)

Phase 4

Hypertonic Saline as a Final Flush and Post-Operative Pain After Single Visit Root Canal Treatment in Mandibular Premolar.

Not yet recruitingNCT07701551

Cairo UniversitySymptomatic Irreversible Pulpitis (SIP)

Start: 2026-08-01End: 2027-01-01Target: 40Updated: 2026-07-14

Unknown Phase

High Volume Plasma Exchange in Children With Acute Liver Failure and Acute on Chronic Liver Failure

CompletedNCT02719210

Institute of Liver and Biliary Sciences, IndiaAcute Liver Failure

Start: 2016-01-01End: 2018-11-30Updated: 2018-12-06

Vasopressin in the Elderly: Physiological Changes in Neuroendocrine Function and Urinary Secretion in Healthy Aging

CompletedNCT06930300

University Hospital, Basel, SwitzerlandHealthy Ageing

Start: 2025-04-30End: 2025-10-10Updated: 2026-01-13

International Multi-center Retrospective Study of Patients With Serum Sodium ≤110 mmol/L to Determine the Relationship Between Osmotic Demyelination Syndrome (ODS) and Rapid Correction of Hyponatremia

Enrolling by invitationNCT07576036

Rochester General HospitalCerebral Edema, Hyponatremia Symptomatic, Osmotic Demyelination Syndrome

Start: 2023-11-01End: 2026-06-30Target: 800Updated: 2026-05-08