Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

PROCEDURE10 trials

Conditions

Adhesion PreventionBowel FunctionsGastric CancerGastro Intestinal CancerHIPECLocally Advanced Malignant NeoplasmMalignant Neoplasm of ColorectumMalignant Neoplasm of Stomach

Phase 1

Hyperthermic Intraperitoneal Chemotherapy for Recurrent Ovarian Cancer

CompletedNCT02672098

Loma Linda UniversityOvarian Cancer

Start: 2016-07-14End: 2023-04-19Updated: 2025-05-22

Adjuvant Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Gastric Cancer

CompletedNCT02672865

Loma Linda UniversityGastric Cancer, Locally Advanced Malignant Neoplasm

Start: 2016-02-02End: 2018-10-03Updated: 2019-04-12

Phase 2

Short-course HIPEC in Advanced Epithelial Ovarian Cancer

CompletedNCT02249013

Professor Fernando Figueira Integral Medicine InstituteOvarian Cancer

Start: 2015-02-28End: 2021-02-23Updated: 2021-03-18

Radical Gastrectomy and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Locally Advanced Gastric Cancer

CompletedNCT02528110

Wuhan UniversityMalignant Neoplasm of Stomach

Start: 2015-08-31End: 2020-03-10Updated: 2020-03-24

Radical Colorectal Resection and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Locally Advanced Colorectal Cancer

CompletedNCT02830139

Wuhan UniversityMalignant Neoplasm of Colorectum

Start: 2016-07-31End: 2020-03-15Updated: 2020-03-18

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Locally Advanced Gastric Cancer

NCT04345770

Wuhan UniversityMalignant Neoplasm of Stomach

Start: 2020-04-01End: 2025-05-31Target: 100Updated: 2020-04-14

Phase 3

Gastrectomy + Cytoreductive Surgery + HIPEC for Gastric Cancer With Peritoneal Dissemination.

Active, not recruitingNCT03348150

The Netherlands Cancer InstitutePeritoneal Carcinomatosis, Stomach Neoplasm

Start: 2017-10-01End: 2027-10-01Target: 102Updated: 2025-07-17

Laparoscopic Gastrectomy With D2 Lymphadenectomy Combined With Hyperthermic Intraperitoneal Chemotherapy (HIPEC) or Not

RecruitingNCT05871099

The Affiliated Hospital of Qingdao UniversityGastric Cancer

Start: 2022-11-20End: 2030-12-01Target: 616Updated: 2026-03-06

Unknown Phase

Effects of HIPEC on Postoperative Bowel Motility and Complications

Active, not recruitingNCT07353177

Peking University People's HospitalAdhesion Prevention, Bowel Functions, Gastro Intestinal Cancer +1

Start: 2025-04-20End: 2026-05-30Target: 193Updated: 2026-01-20

To Evaluate the Feasibility and Safety of Combining Surgery (Pancreatectomy and Cytoreduction) With HIPEC for Treating Pancreatic Cancer With Peritoneal Involvement.

RecruitingNCT07493421

Unidade Local de Saúde São JoãoPancreatic Adenocarcinoma, Peritoneal (Metastatic) Cancer

Start: 2026-03-01End: 2028-10-01Target: 20Updated: 2026-03-25

BMC Cancer2026-03-26

Effect of Hyperthermic Intraperitoneal Chemotherapy on Cytoreductive Surgery in Gastric Cancer With Synchronous Peritoneal Metastases: The Phase III GASTRIPEC-I Trial

Journal of Clinical Oncology2023-10-31107 citations

Quality of life in a phase 2 trial of short-course hyperthermic intraperitoneal chemotherapy (HIPEC) at interval debulking surgery for high tumor burden ovarian cancer

Revista do Colégio Brasileiro de Cirurgiões2020-01-018 citations

388 Short-course HIPEC at the time of interval debulking surgery for high tumor burden ovarian cancer: preliminary results of a pioneering clinical trial in brazil

2019-09-01

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy versus palliative systemic chemotherapy in stomach cancer patients with peritoneal dissemination, the study protocol of a multicentre randomised controlled trial (PERISCOPE II).

2019-05-0685 citations

Neoadjuvant chemotherapy followed by fast-track cytoreductive surgery plus short-course hyperthermic intraperitoneal chemotherapy (HIPEC) in advanced ovarian cancer: preliminary results of a promising all-in-one approach.

2017-12-139 citations

Exploring flow rate selection in HIPEC procedures

Revista do Colégio Brasileiro de Cirurgiões2016-12-017 citations