Hylenex

DRUG7 trials

Sponsors

Halozyme Therapeutics, Vanderbilt University Medical Center, Tissa Hata, MD, Steve Yoelin M.D. Medical Associates, Inc., Pablo Tebas

Conditions

Cardiac OutputDehydrationDermal FillerHealthyHealthy VolunteersPainPediatricsPsoriasis

Phase 1

A Study of the Subcutaneous Injection of a Viscous Antibody Solution With Recombinant Human Hyaluronidase

CompletedNCT00435604

Halozyme TherapeuticsHealthy

Start: 2007-02-28End: 2007-05-31Target: 15Updated: 2011-10-17

The Use of a Recombinant DNA-based Hyaluronidase to Dissolve Fixed Amounts of Hyaluronic Acid Dermal Fillers

CompletedNCT02654522

Steve Yoelin M.D. Medical Associates, Inc.Dermal Filler

Start: 2016-01-31End: 2016-02-29Updated: 2017-05-16

dMAbs for Prevention of COVID-19

CompletedNCT05293249

Pablo TebasHealthy Volunteers

Start: 2022-05-19End: 2025-11-21Updated: 2026-01-22

Phase 2

Effects of Subcutaneous Hyaluronidase Administration on Psoriatic Plaques

CompletedNCT01987609

Tissa Hata, MDPsoriasis

Start: 2015-07-31End: 2018-02-28Updated: 2019-01-04

Phase 3

INFUSE Morphine Study

CompletedNCT00593281

Halozyme TherapeuticsPain

Start: 2006-01-31End: 2006-10-31Updated: 2008-01-14

Phase 4

A Phase IIIB Dose Comparison Study of Subcutaneous Hydration With and Without Human Recombinant Hyaluronidase (HYLENEX) in Volunteer Subjects

CompletedNCT00311519

Halozyme TherapeuticsHealthy

Start: 2005-11-30End: 2006-01-31Target: 50Updated: 2006-04-06

Descriptive Study of Cardiac Output During Rehydration With Recombinant Human Hyaluronidase in Pediatrics

CompletedNCT01139294

Vanderbilt University Medical CenterCardiac Output, Dehydration, Pediatrics

Start: 2010-02-28End: 2011-11-30Updated: 2018-02-01

Related Papers

661. Phase 1, dose-escalation trial of the safety and pharmacokinetics of SARS-CoV-2 DNA-encoded monoclonal antibodies (DMAb) in healthy adults

Open Forum Infectious Diseases2026-01-01

Safety and pharmacokinetics of SARS-CoV-2 DNA-encoded monoclonal antibodies in healthy adults: a phase 1 trial.

2025-10-211 citations